Gene Expression and Regulation in Blastocyst Formation
CHEN Ying, ZHANG Yu-lan, HU Gui-ying (The 2 nd affilicated Hospital of Harbin Medical University, Harbin, 150086)
Blastocyst formation is a crucial stage in early embryo development. Cell junction proteins and cell adhesion associated proteins are involved in the establishment of cell junction and subsequently induce cell fusion, blastocyst formation, differentiation of trophectoderm and mainteinance of blastocyst expansion. Genes regulating development and differentiation participate in the embryo development and differentiation of inner cell mass and trophectoderm, which controls the transition from undifferentiation to differentiation stage. Furthermore, cytokine and growth factor influence the proliferation of cells of inner cell mass. In a word, many proteins and factors participate in the gene expression regulation of blastocyst formation.