Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
Add to Favorite Get Latest Update

Clinical significance of blood endothelin and nitric oxide in patients with chronic renal failure

Jin Xiaohong, Wang Xiaojin, Liu Chuiling, Su Hongyue Department of Internal Medicine and Central Laboratory, Second affiliated hospital, Nanjing Medical University(Nanjing,210000)  
Endothelin(ET) is a very potent vasoconstrictor which can obviously reduce renal blood flow and glomerular filtration rate(GFR) by interacting with ET receptors. Nitric oxide(NO) is a strong vasorelaxing factor which modulates renal blood flow(RBF), GFR and tubular sodium bsorption. The balance of ET and NO influences renal hemodynamics. Twenty nine patients with chronic renal failure(CRF) were enrolled in this study, and 25 health adult set as control. CRF patients were divided into 3 subgroups according to their serum creatinine levels. Plasma ET was measured by radioimmunoassay and serum NO determined by the assay of chromium reduction. RESULTS 〖WTBZ] Plasma ET was significantly elevated in CRF patients(123.3±59.4 BHDW) as compared to the normal control(50.8±7.6BHDW)( P 0.05). It was positively correlated with the degree of renal function impairment and the severity of hypertension. Serum NO was also elevated in CRF patients(84.6±62.6BHDW) as compared to the control(52±13BHDW). No difference was found in serum NO between CRF subgroups with different degrees of renal function impairment. Elevated blood ET and No levels are observed in CRF patients, these changes may be related to the decrement of renal filtration.
【CateGory Index】: R692.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 10 Hits
1 ZHANG Guo Hua, CHEN Xue Gong, LONG Zi Jiang, LI Yun Long, ZHANG Hong Mei (Anhui College of Traditional Chinese Medicine,Hefei 230038);Effects of Wenshen No1 on T and MC in the Shen and Yan deficiency of CRF mice model[J];Anhui Medical and Pharmaceutical Journal;2004-01
2 LI Yong,LING Chang quan(Changhai Hospital Affiliated to the Second Military Medical University,PLA,Shanghai 200433,China);RELATIONSHIP BETWEEN PERIPHERAL BLOOD TNFα, NO AND CHRONIC RENAL FAILURE[J];Journal of Anhui Traditional Chinese Medical College;2002-05
3 Qin Danping,Wu Gang,Liu Yan.(Department of Nephrology,Red Cross Hospital of Guangzhou,Guangzhou 510220);Change of serum nitric oxide after hemodialysis in chronic renal failure[J];Journal of Branch Campus of the First Military Medical;2001-01
4 Li Ruqing (Heze Prefectural People's Hospital,Heze 274031);Effect of Hemodialysis on Content of NO in Blood of Uremia Patients[J];Journal of Heze Medical College;1999-03
5 Qiu Zhiliang, Zhang Fen,Shen Lianglan,et al Department of Nephrology, the Second Affiliated Hospital, Nantong Medical College 226001;The Influence of Hemodialysis on Endothelin in Patients with Chronic Renal Failure[J];Tianjing Medical Journal;1998-04
6 JIN Ling-wei *,DING Hong-xiang,LIU Yi. * The Hemodialysis' Room,Wenzhou Medical College,Wenzhou 325027;Effect of hemodialysis on plasma level endothelin and nitric oxide[J];Journal of Wenzhou Medical College;2001-06
8 Fu Zhao,Zhou Qichang,Fang Ping,et al Ultrasonography Department,2nd xiangya Hospital of Contral South University,Changsha,410011 Hunan;Ultrasonographic Detection of Endothelial Function in Chronic Renal Failure (CRF) Patients[J];Chinese Journal of Ultrasound In Medicine;2002-11
9 MA Ning,TAN Hong,LI Shu-ren.Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050,China[;Hemodynamics changes during cadaveric renal transplantation and the effects of NO on RBF[J];Chinese Journal of Critical Care Medicine;2004-07
10 Zhu Pijiang,Zhou shun,Zhao hua,Wei Xianjin,Shi ronghua Jiang Su Provincial TCM and Western Medicine combined Research Center for Renal Diseases,Zhen Jiang 212002;Studies on Endothelin and Nitrogen monoxide levels in Chronic Renal Failure[J];ZHEJIANG JOURNAL OF INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE;1999-06
Chinese Journal Full-text Database 9 Hits
1 Xiao Zhengxiang; Xu Li(Department of Pediatrics,Xiangya Hospital.Hunan Medical Uniuersity)Liu Shiqun(Department of Pathophysiology,Hunan Medical University;CHANGES AND SIGNIFICANCE OF DT-1IN THE SMALL INTESTINAL REPERFUSION INJURY IN RATS[J];BULLETIN OF HUNAN MEDICAL UNIVERSITY;1995-03
2 Zhang Lianyuan Dong Shuyun Yang Tun Tong Lijia Tang Jian Tang Chaoshu Yang Ye Shi Xiangyun Cheng Shi(Laboratory of Cardiopulmonary Endocrinology, Beijing Medical University, Beijing 100083);Injury-Resistant Action of Metallothionein and Its Relationship with Endothelin[J];Basic Medical Sciences and Clinics;1993-01
3 Wang Rui yin;Zhu Quo bin; Li Jin(Department of Cardiol ogy,The Second Hospital,Shanxi Medical University,Taiyuan 030001);Plasma Endothelin in Patients with Coronary Heart Disease[J];SOUTH CHINA JOURNAL OF CARDIOLOGY;1997-02
4 ;Concentration changes of the plasma endothelin, nitric oxide and 6-keto-prostaglandin-F_1α in patients[J];Shandong Medical Journal;2003-04
5 LIU Shuang 1 LIU Jia 2 ( 1Tianjin Second Central Hospital 300120 2Tianjin 271st Hospital);The Levels of Plasma Endothelin in Patients with Acute Myocardial and Their Significance[J];SHAAXI JOURNAL OF MEDICAL LABORATORY SCIENCES;2000-03
6 WANG Qin,YAO Zhen,Qin Hao.The branch of Liwan Traditional Hospital,Guangzhou 510170,China.;Study of plasma endothelin changes in coronar Artery disease patients before,during and after exercise stress testing[J];Modern Rehabilitation;1999-11
7 LIANG Wei jun,FU Yi bing,CHEN Jian ying(Department of Cardiology,Affiliated Hospital of Guangdong Medical College,Zhanjiang,Guangdong 524001,China);Clinical study of changes in plasma endothelin and tumor necrosis factor levels in patients with coronary heart disease[J];Chinese Heart Journal;2003-02
8 Liu Wanxia 1, Pei Zhuguo 2 1 Department of Nuclear Medicine , Qingdao Municiple Hospital, Qingdao 266011 2Department of Nuclear Medicine, The Second Affiliated Hospital, China Medical University, Shenyang 110003;A study on correlations between endothelin level and parameters of cardiac function in coronary heart disease[J];CHINESE JOURNAL OF THE CARDIAC FUNCTION;1996-04
9 杨连春,王峰,吕敏;NUMERICAL CLASSIFICATION OF CHINESE MEDICINE,ROSE AND SIMILAR SPECIES[J];Journal of General Hospital of Air Force,pla;1996-01
Chinese Journal Full-text Database 10 Hits
1 SHEN Ai Zong, CHEN Fei Hu,WANG Guang Bao,ZHANG Zhen Wei (Pharmacy School,Anhui Medical University,Hefei 230032);Risk factors and interventions involved in the progression of renal disease[J];Anhui Medical and Pharmaceutical Journal;2003-05
2 YANG Mu,DIAO Xiu-zhu,HUANG Ye-hua,REN Wei(Department of Nephrology,Anhui Provincial Hospital Hefei 230001,China);Effect of C-reactive protein on the response to erythropoietin in chronic hemodialysis patients[J];Anhui Medical and Pharmaceutical Journal;2006-08
3 Li Feng,Zhang Xiaoming,Zhang Yun,Ye Chuanhui,Cheng Qingli (Department of TCM,Xijing Hospital,Fourth Military Medicial University,PLA,Xi’an 710032,China);EFFECT OF SHENKANG INJECTION ON LEVEL OF ET 1 AND NO SECRETION IN CULTURED GLOMERULAR MESANGIAL CELL[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;2000-02
4 MA Jian-wei,CAI Qing,LIU Zhan-min,XU Li-mei, CHEN Bao,WEI Han-lin,HOU Jie,DONG Jing (General Hospital of Air force,PLA,Beijing 100036,China);EFFECT OF ZISHEN HUOXUE JIEDU RECIPE ON mRNA EXPRESSION OF ET-1 IN REMNANT KIDNEY OF RATS WITH CHRONIC RENAL FAILURE[J];Journal of Anhui Traditional Chinese Medical College;2001-01
5 Wang Yongjun (Second Attached Hospital of ZheJiang College of TCM, Hangzhou 310006);Combining Chinese Traditional and Western Medicine to Treat Chronic Renal Insufficiency[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1999-01
6 Li Hui,Chai Kefu,Lou Jiwei △ Zhejiang College of TCM,Hangzhou(310053)△Shanghai Meitong Biological Sci tech Co.Ltd.;Experimental Studies of Treating Chronic Renal Failure with Yishen Huoxue Fang[J];Journal of Zhejiang College of Tcm;2000-06
7 LIU Xiao - mei, LI Hui - chun, PAN Li - ping, et al. (Third Hospital of Hebei Medical University, Shijiazhuang 050051, China);Detection of Several Hormones Levels in Chronic Renal Failure Patients before and after Hemodialysis Treatment[J];LABELED IMMUNOASSAYS AND CLINICAL MEDICINE;2000-03
8 Du Yumao (shaanxi College of TCM, Shaanxi);Clinical and Experimental Researches on Chronic Kidney Failure Treated with Zhenwu Decoction[J];;1991-04
9 Yang Xia , et al. (Hunan College of Traditional Chinese Medicine, Hunan);Characteristics of Accompanying Symptoms with Excessiveness of Pathogen in Different Stages with 618 Cases of Chronic Renal Failure[J];China Journal of Traditional Chinese Medicine and Pharmacy;1999-01
10 ZHAO Hong wen, WU Xiong fei, LIU Hong (Division of Kidney,Center of Urology,Southwest Hospital, the Third Military Medical University, Chongqing 400038,China);Effects of some uremic toxins on erythropoietin receptor of CFU-E of rats in vitro[J];Chongqing Medical Journal;2003-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Sun Wansen,Wu Xili,Qiao Chenglin The Second Hospital Attached to Xi'an Jiaotong University,Xi'an (710004);Clinical Study of Gypenodide on Therapeutic Chronic Renal Failure[J];Journal of Zhejiang College of Tcm;2004-02
2 XING Ling-ling,FU Shu-xia,YANG Lin,et al. Department of Nephrology, The Second Hospital,Hebei Medical University,Shijiazhuang 050000, China;Relationship Between TNF-α and IgA Nephropathy[J];Journal of Chinese Physician;2005-02
3 Wang Cai-li, Ma Xiao-Ian, Yin Mei-li, et al. (Division of Nephrology,The First Affiliated of Baotou Medical College,Baotou 014010);Effect of Recombinant Human Erythropoietin on Nitric Oxide, Endothelin-1 in Chronic Hemodiaiysis Patients[J];Chinese Journal of Medicinal Guide;2003-06
4 Qiao Qing, Wei Cui - ying, Tong Guang - ming, et al. (Department of Nephrology,the First Affiliated of Baotou Medical College, Baotou 014010, China);Effect and Clinical Significance of Hemodialysis on Serum Nitric Oxide,Endothelin -1 and Angiotonin Ⅱ in Uremia Patients[J];Chinese Journal of Medicinal Guide;2004-06
5 Qin Danping,Wu Gang,Liu Yan.(Department of Nephrology,Red Cross Hospital of Guangzhou,Guangzhou 510220);Change of serum nitric oxide after hemodialysis in chronic renal failure[J];Journal of Branch Campus of the First Military Medical;2001-01
6 Wang Caili, Qiao Qing, Zhi Shengli Division of Nepheology, The First Affiliated of Baotou Medical College, Baotou (014010);Effect of Recombinant Human Erythropoietin on Serum Nitric Oxide Contents in Patients on maintenance Hemodiaiysis[J];Journal of Radioimmunology;2003-04
7 LONG Ruoting,HE ZeyunYiyang Health School,Yiyang (410000);The Study the Effects of Yishen Tang on Pathological Changes and Col-Ⅳ and MMP-2 Expression with 5/6 Nephrectomy Rats[J];Chinese Journal of Integrated Traditional and Western Nephrology;2006-06
8 ZHANG Yong,XIAO HouQin,ZHANG JieE,et al.Division of Nephrology,The Affiliated Taihe Hospital of Yunyang Medical college,Shiyan 442000,China;The protective and therapeutic effects of Gypenosides in patients with early stage chronic renal failure[J];Journal of Clinical Internal Medicine;2007-10
9 Ding hongxiang, et al;Plasma levels of nitrogen monoxide (NO) and endothelins (ET-1) in hemodialysis patients[J];Zhejiang Clinical Medical Journal;2001-04
10 NI Dao-lei1,SHENG Mei-xiao2(1.Nanjing University of Chinese Medicine,Nanjing 210029,Jiangsu,China;2.Jiangsu Hospital of Traditional Chinese Medicine,Nanjing 210029,Jiangsu,China);Mediums of Leading Cardiovascular Complication of Chronic Renal Failure[J];Journal of Liaoning University of Traditional Chinese Medicine;2008-12
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved