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《LISHIZHEN MEDICINE AND Materia MEDICA RESEARCH》 2007-09
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Experimental Study on Treating Chronicrenal Failure with Humulus scandens Merr.in Rats

ZHOU Yu-juan~1 WANG Yong-qi~2 LI Shao-chun~1 LIU Li~1 WANG En-jun~1 LIU Chun-ying~1 LIU Xin-xia~1 GENG Xian~1 (1.Department of Pharmacology of Hebei University,Baoding 071000,China; 2.Xushui Hospital,Xushui,Hebei 072550,China)  
Objective To observe the effect of Humulus scandens Merr.(HSM) on chronic renal failure (CRF).Methods The rats were fed with adenine to establish the chronic renal insurfficient anemia model,and then they were divided into three groups separatedly fed with HSM(high or middle dosage) and Shenshuaining capsule,and then the levels of BUN and Scr,and Na~+, K~+,Cl~- were observed.Results HSM could significantly decrease serum levels of BUN and Scr,ameliorate the electrolyte.Con- clusion HMS has therapeutic action on CRF in rats.
【Fund】: 河北省保定市科学技术研究计划资助项目(No.99F008)
【CateGory Index】: R285.5
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