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《Lishizhen Medicine and Materia Medica Research》 2008-12
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Combinational Technology of Separation,Selection and Identification on Active Composition of Chinese Traditional Herb and Molecular Imprinting Technology

LI Jian-yong1,YANG Ya-jun1,ZHANG Ji-yu1,CAI Xue-peng2(1.Lanzhou Institute of Animal Science and Veterinary Pharmaceutics,Key Lab of New Animal Drug Project,Chinese Academy of Agricultural Sciences,Lanzhou 730050,China;2.Lanzhou Institute of Veterinary Science,Chinese Academy of Agricultural Sciences,Lanzhou 730050,China)  
It is an important aspect of modernization for Chinese traditional herb that active composition of Chinese traditional herb is studied with modern science and technology.Affinity chromatography is prepared through molecularly imprinted polymers(MIPs).Based on high performance of chromatographic separation technology and highly sensitive and special combinational analysis ability of mass spectrogram,MIP-HPLC-MS is connected.Therefore,active composition from Chinese traditional herb may be separated,selected and identified,which realized combinational technology of separation,selection and identification for active composition of Chinese traditional herb.The mechanism of molecular imprinting technology(MIT) and synthetic processes of MIPs were introduced in this paper.Application of MIT for separation,selection and identification for active composition of Chinese traditional herb were summarized,and the trends of MIT were also discussed in this paper.
【Key Words】： Active composition of Chinese tradational herb Combinational technology of separation selection and identification Molecular imprinting technology
【Fund】： 国家自然基金项目(No.30771590);; 中国博士后科学基金第42批博士后科学基金项目(No.20070420443)
【CateGory Index】： R284
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