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《Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine》 2004-02
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Effects of Puerarin on Plasma Endothelin and Nitric Oxide in Diabetic Patients with Microvascular Complications

Huang Lie-hu,Ye Rong,Lin Xi-min  
Objective: To evaluate the effects of puerarin on plasma endothelin and nitric oxide in diabetic patients with microvascular complications. Methods: Base treatments of all 46 cases were same, but the treatment of puerarin group was set up as follows: 400mg puerarin in 250mL 5% GNS, ivgtt, qd, every 15 days was taken as treatment course. The plasma ET and NO was measured before and after the treatments.Result: After the treatments, ET in puerarin group was significantly lower and NO was markedly higher (P 0.01). Compared with control group, ET and NO after treatments in puerarin group changed markedly (P 0.01). Conclusion: Puerarin can decrease plasma ET or increase NO in diabetic patients with microvascular complications.
【CateGory Index】: R587.1
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1 LU Sijia.Department of Cardiology,People's Hospital of Hainan,Haikou 570312,China;Puerarin injectiom in treatment of patients with unstable angina pectoris[J];Clinical Medicine;2011-02
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