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《Journal of Reproductive Medicine》 2001-04
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Differential diagnosis and management of ambiguous genitalia

TIAN Qin jie, HE Fang fang, DENG Cheng yan, YU Qi, GE Qin sheng Division of Reproductive Endocrinology, Department of Obstetrics & Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730  
Objective: To study the eitology, differential diagnosis and management of am biguous genitalia. Mehtods: 105 cases of ambiguous genitalia with disorders of sexual differentiation were analyzed basing on the study of clinical characteristics and basic research. Results: Ambiguous genitalia are closely related to the function of androgen. It could be classified into 3 groups: androgen excess, androgen deficiency and failure of gonadal differentiation. Differential diagnosis depends on clinical manifestations, chromosome examination, serum hormone determination, final operation, pathology and receptor study etc. Management relied on the correct diagnosis and specific conditions of the patients. Conclusion: The correct and early etiological diagnosis is the key for the management of ambiguous genitalia.
【Key Words】: Hermaphroditism Androgen Chromosome
【CateGory Index】: R447
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