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《Journal of Instrumental Analysis》 2006-02
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Determination of Artemisinin by Capillary Electrophoresis with Conductivity Detection

HUANG Bao-mei~1,YAO Cheng-wei~2(1.Chemical Department of Mianyang Normal University,Mianyang 621000,China;2.The 4th Institute of CARDC,Mianyang 622653,China)  
A new method for the determination of artemisinin in artemisia annna L.is established by high performance capillary electrophoresis using self-designed conductivity detection system in this paper.Important experimental parameters including organic additive(ethanol) concentration,the types and concentrations of the buffering solution,acidity,injection time and working voltage are systematically investigated.Under the optimal conditions(Tris-H_3BO_3 buffering solution,H_3BO_3 1.5 mmol/L,pH=9,and 15 kV working voltage),a linearity is established between peak height(Y) and the mass concentration of(ρ) in the range of 20-280 mg/L.The detection limit is 3.2 mg/L.
【CateGory Index】: O658.9;TQ464
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【References】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Ben ZOU Ting WANG Jian-wen School of Pharmacy, Soochow University, Suzhou Jiangsu 215123, China;Recent Development on Artemisinin Determination in Artemisia annua L.[J];Anti-Infection Pharmacy;2008-04
2 Zhou Lijuan,Liu Qingfei,Wang Yiming,Luo Guoan(Department of Chemistry,Tsinghua University,100084 Beijing);Capillary Electrophresis and Its Applications in TCM Research[J];World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica;2007-02
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 XIA Yu-jie1,2, ZENG Jian-li1,2, ZHAO Bing1 (1. State Key Lab. Biochem. Eng., Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; 2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China);Extraction of Artemisinin from Artemisia annual L. with 1-Ethyl-3-methylimidazolium Bromide Enhanced by Ultrasonic Wave[J];The Chinese Journal of Process Engineering;2008-04
2 ZHANG Rong-shu1,2,ZHAO Min1,HAN Song1,3(1. Life Science College of Northeast Forestry University,Harbin 150040,China;2. Second Clinical Medical Institute of Qiqihar Medical College,Qiqihar 161006,China;3. Heilongjiang Institute of Pharmaceutical Industry,Harbin 150040,China);Study on Contents of Artemisinin in Artemisia annua L. Introduced from Different Provenances[J];Chemistry and Industry of Forest Products;2008-06
3 ZHANG Rong-shu1,3,WANG Yan2,ZHAO Min1(1.Life Science College of Northeast Forestry University,Harbin 150040,China; 2.Science Research Center,Harbin Institute of Technology,Harbin 150001,China; 3. Second Clinical Medical Institute of Qiqihar Medical College,Qiqihar 161006,China);Analysis of Artemisinin from Artemisia annua L. by HPLC-UV Using Pre-column Derivatization[J];Chemistry and Industry of Forest Products;2009-03
4 CHEN Jing1,ZHAO Rui2,CHEN Jun2,ZENG Yi-mei1,LI Xian1,WANG Jin-hui1 (1.School of Traditional Chinese Materia Medica,Shenyang,Pharmaceutical University,Shenyang 110016,China;2.Horticulture College,Shenyang Agricultural University,Shenyang 110000,China);Determination of artemisinin and its related sequiterpenoids in leaves of Artemisia anuua at full flowering by HPLC-UV-ELSD[J];Journal of Shenyang Pharmaceutical University;2008-11
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Wang Zongde 1 Sun Fanghua 2 (1College of Forestry, JAU, Nanchang330045;2Luxi Forestry station of Jishui County Jiangxi Province, Jishui331600);The Progress of Studies on Physical, Chemical Characters and Determination of Artemisinin[J];ACTA AGRICULTURAE UNIVERSITIS JIANGXIENSIS;1999-04
2 FENG Cheng-qiang,ZHANG Yi-ling,ZHANG Wen-sheng,MENG Fan-yun,HAN Jian-ping(Institute of Natural Medicine and Chinese Medicine Resources,Beijing Key Laboratory of Protection and Utilization of Chinese Medicine,College of Resource Science & Technology,Beijing Normal University,Beijing 100088);Identification of Gardenia jasminoides Ellis and Gardenia jasminoides Ellis var.grandiflora Nakai by HPCE[J];Journal of Beijing University of Traditional Chinese Medicine;2006-05
3 ZHAO Bing; WANG Yu-chun; WU Jiang; OUYANG Fan(State Key Lab. Biochem. Eng., Inst. Chem. Metall., CAS, Beijing 100080, China);Extraction of Artemisinin Enhanced with Ultrasonic Wave[J];ENGINEERING CHEMISTRY & METALLURGY;2000-03
4 YU Yan-Li ①,PAN Han-Qing,JING Li ②,GU Qing ③ ( ①Department of Pharmcy,Jinan Military General Hospital of PLA,Ji’nan 250031,Shandong China) ( ②Department of Pharmcy,Changhai Hospital,Second Military Medical University,Shanghai 200433 China) ( ③The Huai-yin People Hospital of Jinan City,Ji’nan 250021,Shandong China);Determination of Scopolamine and Aconitine in Bitongning patch By High Performance Capillary Zone Electrophoresis[J];Pharmaceutical Journal of Chinese People's Liberation Army;2005-01
5 LIU Ping~①,GU Jin,FENG Jian-Yong~② (~①TCM Pharmacy of Chinese PLA General Hospital,Beijing 100853 China) (~②Department of Pharmacology.The Fist Military Medical University,Guangzhou 510515,Guangdong China);Identification of Bezoar Artificial Bezoar Gallstones in Mans and Another False Bezoar by HPCE[J];Pharmaceutical Journal of Chinese People's Liberation Army;2005-04
6 Qian Guoping,Yang Yiwen,Wu Caijuan,Ren Qilong (National Laboratory of Secondary Resources Chemical Engineering, Zhejiang University, Hangzhou 310027);Supercritical CO_2 Extraction of Artemisinin from Artemisia annua L.[J];Chemical Industry and Engineering Progress;2005-03
7 Liu Chunzhao,Wang Yuchun,Ouyang Fan (State Key Laboratory of Biochemical Engineering,Institute of Chemical Metallurgy, Chinese Academy of Sciences,Beijing 100080) Ye Hechun,Li Guofeng (Institute of Botany,Chinese Academy of Scien;ADVANCE IN ARTEMISININ BIOSYNTHESIS RESEARCH[J];Natural Product Research and Development;2000-01
8 HOUJing-guo,WANG Zhu-ming,HE Tian-xi,DUXin-zhen,GAO Jing-zhang (College of Chemistry&Chemical Engineering,Northwest Normal University,Lanzhou730070,China);Chiral Separation of Pilocarpine by Capillary Electrophoresis[J];Journal of Instrumental Analysis;2004-01
9 Tan Ping, Zhang Guohua, Xiao Shaoyu (Department of Parasitology, Medical College to Wuhan Science and Technology University, Wuhan 430080);IN VITRO EFFECT OF ARTEMETHER ON TRICHOMONAS VAGINALIS[J];JOURNAL OF PRACTICAL PARASITIC DISEASES;2000-01
10 ZHOU Jie-yu,ZHANG Chong-wei,XU Xue-shu*,LU Yan-hua, WEI Dong-zhi (State Key Laboratory of Bioreactor Engineering, East China Uninersity of Science and Technology, Shanghai 200237, China);Chiral Separation of Hesperidin by Capillary Electrophoresis[J];Food Science;2006-05
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Ben ZOU Ting WANG Jian-wen School of Pharmacy, Soochow University, Suzhou Jiangsu 215123, China;Recent Development on Artemisinin Determination in Artemisia annua L.[J];Anti-Infection Pharmacy;2008-04
2 XUE Hong-bao,JIAO Yan-na,PANG Guo-wei,LIU Hai-feng,TANG Jing,LI Hui(School of Chem.Eng.,Sichuan Univ.,Chengdu 610065,China);Simultaneous Quantitative Analysis of Six Ingredients in Artemisia Annua L. by HPLC[J];Journal of Sichuan University(Engineering Science Edition);2009-04
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