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《Journal of Instrumental Analysis》 2010-01
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Progress on Construction and Research of Sensing Films of Molecularly Imprinted Electrochemical Sensors

CHEN Zhi-qiang,LI Jian-ping,ZHANG Xue-hong,JIANG Fu-yang(College of Chemistry and Bioengineering,Guilin University of Technology,Guilin 541004,China)  
Molecular imprinting technique(MIT) has been widely applied in chromatographic separation,solid phase extraction,biomimetic sensor,enzymatic catalysis and membrane separation,etc.In recent years,molecularly imprinted electrochemical sensors(MIECS) have been received more and more attentions.Combining with characteristic of electrochemical technique and MIT,MIECS offered significantly lower detection limit and low cost with the possibility of easy miniaturization.For the MIECS,molecularly imprinted sensing film must combine with transducer effectively in order to recognize and analyze the targe molecules.So construction of appropriate molecularly imprinted sensing film system is very important for the design of MIECS.In this paper,detection principle and classification of MIECS have been introduced.The construction methods and characteristic of five kinds of sensing film systems,including traditional system,self-assembly system,molecularly imprinted polymer particles embedded system,electro-polymerized system and sol-gel system,were introduced,and theri application were summarized.The prospects development of MIECS was viewed.
【Key Words】： molecularly imprinted electrochemical sensor construction of sensing film review
【Fund】： 国家自然科学基金资助项目(20665003);; 广西自然科学基金资助项目(0728214);; 广西环境工程与保护评价重点实验室研究基金资助项目(桂科能0701Z001)
【CateGory Index】： TP212.2
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