Experimental study on protective effect of Danshen for the cultured epithelial cells from injury by oxidized low density lipoprotein
XU Dong-Bo,ZHANG Jun-Ping,ZHANG Wen-Zhi,ZHANG Zhi-Yao,QIU Jin-Ming(Department of Pathology, Tianjin Medical University, 300070)
Objective: To study the protective function of Danshen on the oxidative injury. Methods: The epithelial cells were cultured with Danshen before or after contacting with oxidative LDL(O-LDL).MDA, SOD, GSH-Px were measured in the culture medium and homogenate of epithelial cells. The cellular proliferation were observed by the method of MTT. Results: In the groups that cells were cultured with Danshen before or after exposing to the O-LDL, the concentration of SOD and GSH-Px were much higher than the groups that cells were directly contacted with O-LDL, but MDA was much lower, and they also had a lower cellular proliferation degree. Conclusion: Danshen can protect the epithelial cells from the oxidative injury.
【CateGory Index】： R285.5