Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Tianjin Medical University》 2003-02
Add to Favorite Get Latest Update

The diagnostic utility of combined determination of CYFRA21-1,NSE,CEA,β_2-MG in patients with lung cancer

ZHANG Wei,CHEN Ying,ZHANG Peng(Cancer Institute & Hospital of Tianjin Medical University,Tianjin 300060,china)  
Objective: To explore the combine determination of CYFRA21-1,NSE,CEA?β2-MG in serum to improve the positive rate in detection of lung cancer,and offer the evidence for clinical diagnose and therapy in early stages.Methods: Serum levels of CYFRA21-1,NSE,CEA?β2-MG were obtained in 155 cases of lung cancer,72cases of benign lung disease and 50 cases of normal by electric chemilluminescent and immunonephelometric method. Results:The combined determination of four tumor markers in the group with lung cancer had a higher positive rate than control.The highest positive rates were 77.7% for CYFRA21-1 in the detection of squamouscell carcinoma,78.4%for NSE in small cell lung cancer,and they were significantly difference from the other patterns of lung cancer respectively.Conclusion: They are reliable tumor markers in diagnosing lung cancer,and helpful to improve the diagnostic positive rate,sensitivity and accuracy.
【CateGory Index】: R734.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 DU Tong xin,WANG Zi zheng,TIAN ren Nanjing First Hospital affliated to Nanjing Medical University,Nanjing 210006,China;Changes of NSE,CYFRA21-=1 and CEA in Patients of Lung Tumor[J];CANCER RESEARCH ON PREVENTION AND TREATMENT;2000-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Pang Baozhong,et al. Qingdao Tumor Hospital,Qingdao 266042;The Clinical Value of CYFRA21-1 and NSE in Lung Cancer Patients who were Testea by IRMA[J];Qingdao Medical Journal;1999-06
2 Wang wei,Lu Zhiwei,Huang Xiaochun,et al;Study on biological markers detection of lung cancer[J];Shandong Medical Journal;2002-04
3 Zhang Xaoshi,Zhou Xiong,Wang Hongchun;Diagnostic value of cytokeration 19 fragment 21-1, carcinoma associated antigen and neuron-specific enolase in lung cancer[J];Shandong Medical Journal;2004-07
4 CHEN Hu-yun,JIANG Xian-yong,CHEN Jie,et al.(Department of Medical Laboratory,Affiliated Hospital of Xiangnan University,Chenzhou 423000,Hunan,China);Diagnostic Utility of Combined Determination of CYFRA21-1,NSE,CEA,and β_2-MG in Patients With Lung Cancer[J];Practical Preventive Medicine;2007-04
5 SUN Xin-ping,HUANG Wei-kun,ZHANG An-ping,ZHU Zong-xun,ZHAO Wen-peng,LIU Kun(Department of Surgery,Gansu Provincal Corp Hospital,Chinese People's Armed Police Forces,Lanzhou 730050,China);The prognostic action of chest computed tomographic(CT) and tumor marker of non small lung cancer N 2 lymphatic metastasis[J];Acta Academiae Medicinae Cpapf;2003-04
6 FAN Xiao-yun, WANG Qi-fu, LUO Jia-lun(The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China);Diagnostic Value of Combined Detection of Serum NSE, CYFRA21-1 and CEA in Lung Cancer[J];Journal of Oncology;2004-03
7 LIU Yucheng,Xu Chunling,Miao Zhongchang,et al. Department of Radiology,No 1 People's Hospital,Lian Yungang,Jiangsu Province 222002, China;The value of CT scancombined with estimation of serum tumor markers in the diagnosis of pulmonary solitary lesion[J];Shanghai Medical Imaging;2005-01
8 SHI Chunlei,ZHANG Xueyan,HAN Baohui,et al.Department of Pulmonary Disease,Shanghai Chest Hospital,Shanghai(200030);Detection of Serum Carcinoma-embryo Antigen,Neuron Specific Enolase and CYFRA21-1in Diagnosis of Lung Cancer[J];Journal of Diagnostics;2003-03
9 Wang Liping Ruan Qiao Gong Yanping et al Department of Oncology First affiliated Hospital of Henan Medical University Zhengzhou;Clinical Value of Serum CEA,CA125,Gastrin and NSE in Patients with Lung Cancer[J];Chinese Journal of Clinical Oncology;2001-07
10 LI Jin-zhou, HONG Xi-tian , BAI Xian-hong(Henan Tumor Hospital , Zhengzhou 450008,China);The Role of Combination of Serum Carcinoma-embryonic Antigen,Neuron Specific Enolase and Cytokeratin 19 Fragment Detection in Diagnosis for Lung Cancer[J];Bulletin of Chinese Cancer;2005-04
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 SONG Li hua,SONG Xian rang,ZHANG Xi qin,et al.Shandong Tumor Hospital & Institute,Jinan 250117,China;Value of CEA,NSE and CYFRA21-1 in Patients with Advanced Lung Carcinoma[J];Journal of Qilu Oncology;2003-03
2 Han Jun; Xu Liangzhong; Zhu Xiongzeng(Department of Pathology. Cancer Hospital. Shanghai Medical University, Shanghai 200032);TISSUE DISTRIBUTION AND INTRA CELLULAR LOCALIZATION OF THE MULTIDRUG RESISTANCE GENE PRODUCT P-GLYCOPROTEIN IN NORMAL HUMAN TISSUES[J];JOURNAL OF SHANGHAI MEDICA(UNIVERSITY);1997-02
3 LIU Wei-Jun, DING Jian (Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 200031);Molecular Mechanisms Involved in the Regulation of Telomerase Activity[J];Progress In Physiological Sciences;2001-03
4 Wang Jin-Qing;Fan Mu-Zhen (Department of Biochemistry,China-Japan Friendship Institute of Clinical Medical Sciences,Beijing 100029);The Regulation of the Inhibition of Polyamine Biosynthesis to the Expression of c-Ha-ras Oncogene in Transformed Cells[J];;1995-03
5 LU Qin,WU De- ming,GUAN Weiling,et al. The Fourth People's Hospital of Suzhou; 215001;Expression and significance of P-gp,Topo Ⅱ and GST-π in colorectal carcinoma[J];Jiangsu Medical Journal;2002-01
6 DAI Jianhua,LI Guoren,LIU Xiaofeng,MIAO Fulu,CHEN Guanghui,SHAO Zhongfan, WANG Yanqmg, BAI Ling. Department of Thoracic Surgery, First People' s Hospital of Lian yungang, Jiangsu 222002;Clinical Significance and Expression Level of Associated Multi-drug Resistance Gene in Esopnageal or Cardiac Cancer Tis-sues[J];The Journal of Medical Theory and Practice;2002-02
7 Long Jiang,Fu Deliang, Xu Jin, et al. The Center for Pancreatic Cancer, Huashan Hospital,Fu Dan University, Shanghai 200040, China;Effect of preoperative intra-arterial infusion chemotherapy on patients with pancreatic cancer[J];Chinese Journal of Practical Surgery;2004-05
8 XUE Jun,ZHI Xue-jun,ZHANG Zhen-zhong,et al. Department of General Surgery,First Affiliated Hospital,Zhangjiakou Medical College,Zhangjiakou 075000,China;Study on the expression of drug-resistant markers P-gP and HSP in gastric and esophageal carcinomas[J];Chinese Journal of Clinkal Oncology and Rehabilitation;2002-01
9 MA Qiang, ZHANG Zhenshu, WANG Qunying, et al. Department of Gastroenterology, Nafang Hospital, First Military Medical University, Guangzhou 510515, China;Establishment and expression of multidrug resistance-related genes of human colon carcinoma LoVo/Adr cell line[J];Chinese Journal of Digestion;2002-07
10 WANG Qi-jun,ZHU Wei-xing,XING Xiu-mei,et al. (Beijing Institute for Cancer Research,Beijing 100034,China);The Trend of Cancer Incidence in Urban Beijing from 1982 to 1997[J];Bulletin of Chinese Cancer;2001-09
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved