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《Chinese Journal of Traditional Medical Science and Technology》 2002-06
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EXPERIMENTAL STUDY ON THE EFFECT OF ELECTROACUPUNCTURE ON VASOACTIVE INTENSTINAL PEPTIDE IN RAT WITH GASTRIC MUCOSAL DAMAGE

Shen Guo-ming,et al (Anhui College of Traditional Chinese Medicine,Hefei 230038)  
Objective:To study the effect of electroacupuncture(EA) of Zusanli (ST 36) on vasoactive intestinal peptide(VIP)levels in rats with gastric mucosal damage.Methods:40 Wistar rats were randomly divided into 4 groups:normal control group,model group(group with gastric mucosal damage,GMD),EA group(with EA Zuasnli +GMD),non-point group(with EA+non-point+GMD).The model of gastric mucosal damage was induced by restrained-cold stress.Gsatric mucosal blood flow(GMBF)were measured by the method of "hydrogen gas clear".Contents of VIP in plasma,antrum and medulla were determined by radiooimmunoassay. Results:In comparison with control group,GMBF of model group decreased significantly(P0 01);while contents of VIP in plasma,antrum and medulla lowered obviously(P0 05).Compared with model group,contents of VIP and GMBF in EA group increased significantly(P0 01);whereas LI decreased obviously(P0 01) Conclusion:EA at Zusanli (st36) can protect gastric mucosa from injury in stress rats.VIP may play a certain role in the protective effect of electroacupuncture on the gastric mucosal damage.
【CateGory Index】: R245.97
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