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《Journal of Audiology and Speech Pathology》 2004-05
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Diagnostic Value of DPOAE During Glycerol Test in Early Endolymphatic Hydrops

Bie Xu~, Li Xujing, Lv Hongguang, et al. (()~Department of Otolaryngology, the second affiliated hospital, Dalian Medical University, Dalian,116027,China)  
Objective The motive of this investigation is to use DPOAE combined with glycerol test to find the change of cochlear function with early endolymphatic hydrops in probable Meniere's disease. Methods The patients with probable Meniere's disease (40 ears)and the control group with normal ears(34 ears) were tested with distortion product otoacoustic emission(DPOAE) and were recorded before and 1 hour after oral administration of the glycerol.Results In normal group the glycerol test had no effect on every frequency of both the level, S/N ratio of DPOAE. For patient group themselves to compare before with after administration of the glycerol,the level and S/N ratio of DPOAE at 0.5KHz had significant changes among all of the frequencies(P0.05). To compare patient group with normal group, patient group showed significant changes in the level and S/N ratio of DPOAE at 0.5 kHz and the S/N ratio at 1.0 kHz(P0.05). We also find there were a certain positive linear trend between the level and S/N ratio of DPOAE.Conclusion We can use DPOAE glycerol test to offer an objective basis for an early diagnosis in patients with probable Meniere's disease; When using this detection, the changes of S/N ratio should be paid more attention to.
【CateGory Index】: R764.04
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