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《Journal of Isotopes》 2005-04
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Labeling of Annexin V With ~(125)I and Its Biodistribution in Mice

JIN Cai-ling~1,XU Yu-jie~1,FAN Wo~1,HUA Zi-chun~2,HU Ming-jiang~1,WANG Dao-jin~1,ZHU Ran~1,ZHANG You-jiu~1(1.School of Radiation Medicine and Public Health,Suzhou University,Suzhou 215007,China; 2.State Key Laboratory of Medical Biology Technology,Nanjing University,Nanjing 210093,China)  
Annexin V is labeled with ~(125)I by using Iodogen method and the biodistribution of which in mice is investigated.The labeling yield of ~(125)I-Annexin V is 94.9% and its radiochemical purity is over 99% after parification.The radioactivity uptake is the highest in kidney,followed in order by blood,liver,heart,lung and spleen;no uptake in brain;the lower in muscle and bone;The uptake of the selected tissues is decreased rapidly at 1 hour after injection except blood.The results show that it is a excellent imaging agent for diagnoses.
【Fund】: 江苏省高校自然科学基金(04KJB350130);; 江苏省核医学与生物技术重点实验室开放基金(KJS01010)资助项目
【CateGory Index】: R817
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3 DING Cheng-shi SHEN Ye-shou LI Geng WEI Zi WEI Feng (Institute of Biochencistry and Nicrobiology,Anhui University,Hefei 230039,China);Study of a glycoprotein from Gastrodia elata:its effects of anticoagulation and antithrombosis[J];China Journal of Chinese Materia Medica;2007-11
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1 KONG Xiang ying,XIAO Tao yuan,BAI Jia si. (Department of Pediatrics,Southwest Hospital,the Third Military Medical University,Chongqing 400038,China);Influence of hyperbaric oxygen on ultrastructure and apoptosis of neonatal rats brain[J];Chongqing Medical Journal;2004-04
2 ZHANG Jin-shan (Department of Nuclear Medicine,Guangzhou Second People's Hospital,Guangzhou510150,China);Apoptosis radionuclide imaging[J];Foreign Medical Science.Section of Radiation Medicine and Nuclear Medicine;2004-01
3 Hu Zhibing, Zheng Deshu,Lu Xuefen ,et al (Institute of Neuroscience, Guangzhou Medical College, Guangzhou 510182);The Establishment of an Experimental Model of Neonatal Hypoxic-ischemic Encephalipathy in Rat[J];ACADEMIC JOURNAL OF GUANGZHOU MEDICAL COLLEGE;1999-03
4 Shi Yiting,Zhao Yi,Zhang Xingdong,et al.Department of Neurology,the Affiliated Tengzhou Central People's Hospital of Jining Medical College,Tengzhou 277500;Experimental study on relationship between expression of Bax and Bcl2 in perifocal tissue in cerebral hemorrhage and neuron apoptosis[J];Chinese Journal of Practical Neruous Diseases;2006-02
5 WANG Hua,MENG Bin,WU Bao min,et al (Department of Pediatrics,The Second Clinical College of China Medical University,Shenyang China 110004);The early changes of cerebral microcirculation after hypoxic-ischemic brain damage in newborn rats[J];Pediatric Emergency Medicine;2002-01
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7 LIU Ya-jun~1,CUI He~2,XIE Dong-ping~1,MIAO Bing~1,LIU Ke-jing~1,CHEN Lian-bi~1(1.Institute of Physiology,School of Medicine,Shandong University,Jinan 250012,Shandong,China;2.Department of Physiology,Shandong Medical College,Jinan 250022,Shandong,China);The role of bcl-2 and bax in the protection of hippocampal neurons by cerebral ischemic preconditioning against ischemia/reperfusion injury[J];Journal of Shandong University(Health Sciences);2006-03
8 Wang Wei, Shen Xinya *, Kang Zhonghan, Zhao xiaozhen, Xu jianwen (Department of Anatomy, Fujian Medical University, Fuzhou 350004; *Department of Anatomy, Shanghai Medical University, Shanghai 200032);CORRELATION WITH ACTIVITY OF TISSUE-TYPE PLASMINOGEN ACTIVATOR AND EXTRACELLULAR MATRIX IN BRAIN OF NEONATAL RATS ON HYPOXIA ISCHEMIA[J];Chinese Journal of Neuroanatomy;2002-01
9 Center of Perinatology, the First Affiliated Hospital of Jinan University(Guangzhou 510632) Zhang Yun Wang Zineng Miao Zhulin;Ultrastructural study on the neuron degeneration forms of hypoxic-ischemic encephalopathy in neonatal rats[J];Shaanxi Medical Journal;2005-01
10 JIANG Li, TANG Yunzhen,HUANG Xiaoming,Department of Pediatrics, Affiliated Zhongda Hospital, Southeast University Medical College, Nanjing 210009,P.R.C;Observation of neuron apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat[J];JOURNAL OF APPLIED CLINICAL PEDIATRICS;2000-04
【Secondary Citations】
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1 LI Chun-jian, HUANG Jun, YANG Guo-ping1, XU Yi-nan2, LU Lin2, FENG Zhen-qin3 (Department of Cardiology, 1Department of Animal Experiment; 2Center of the Clinical Experiment, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Nanjing 210;An Animal Model of the Femoral Artery Thrombosis in Rabbits by Balloon Injury[J];Acta Universitatis Medicinalis Nanjing;2001-04
2 FAN Yao, WANG Jin, YANG Shan, YANG Xiang, ZHANG Li Na, HUA Zi Chun, ZHU De Xu (The State Key Laboratory of Pharmaceutical Biotechnology,Department of Biochemistry, School of Life Science, Nanjing University, Nanjing 210093, China);Molecular Dynamics Simulation of Docking a Novel Hirudin-like Anti-coagulant Protein to Thrombin[J];Progress In Biochemistry and Biophysics;2001-01
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