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《Journal of Isotopes》 2013-03
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Determinate the BPA in Biological Samples by Spectrophotometry

LI Feng-lin,LUO Zhi-fu,DENG Xin-rong,FAN Cai-yun,LIU Zi-hua,WU Meng(Department of Isotopes,China Institute of Atomic Energy,Beijing 102413,China)  
Boron neutron capture therapy(BNCT) is a new radiation therapy,of which clinical interest has focused primarily on the treatment of high-grade gliomas.At present,the most effective drug for BNCT is p-Boronophenylalanine(BPA),becouse it has little side effect and low toxicity,persisted longer in tumors compared with related molecules.The method of 3-Methoxy-Methylenimine H spectrophotometry was established to measure the concentration of 10B in biological samples.The biodistribution of the BPA was studied in normal mice.
【CateGory Index】: R96;O657.3
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