The relationship between curcumin and non-alcoholic fatty liver disease
YU Yuanjie;TAN Shiyun;Department of Gastroenterology,Renmin Hospital of Wuhan University;
Non-alcoholic fatty liver disease( NAFLD) is one of the most common chronic liver diseases,its disease spectrum contains simple steatosis,non-alcoholic steatohepatitis( NASH),fibrosis,cirrhosis and hepatocellular carcinoma( HCC). The pathogenesis of NAFLD is rather complicated,both insulin resistance( IR) and oxidative stress involved in its occurrence and progress. NF-κB singnal pathway activation could be a crucial mechanism. Recently,curcumin has been an increasingly hot spot in medical field,due to its multiple pharmacological effects,such as regulate hyperlipidemia,antioxidant,anti-inflammation,hepatic protection. Based on numerous evidences of studies,curcumin has enormous potential to be one of the therapeutic drugs for NAFLD. This review focused on research status about the potential relationship between curcumin and NAFLD.
【CateGory Index】： R575.5