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Assessment of T Cell Subset and Natural Killer Cell Activity in Liver Cirrhosis and Primary Hepatic Carcinoma

Yao Shukun Li Sheng-mian Li Zhihui et al(Fourth Affiliated Hospital,Hebei Medical University Shijiazhuang 050011)  
? Aim: For understanding the cellular immune function of patients with liver cirrhosis (LC) and primary hepatic carcinoma (PHC).Method:T cell subset and natural killer (NK) cell activity in patients with LC and PHC were assessed with flow cytometry.Result:The result revealed that CD+3 cells,CD+4 cells and NK cell activity in LC group were significantly decreased compared with control group,and those in PHC group were fewer than those in LC group.The CD+4 to CD+8 ratio in LC group and PHC group was also decreased.A higher incidence of infection was observed in the two groups.conclusion:The conclusion indicates that the cellular immune function was seriously impaired in patients with LC and PHC.To monitor the immune index above may guide the assessment of prognosis and the choice of rational therapy.
【CateGory Index】: R735.7
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