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《Journal of Wuhan Institute of Technology》 2009-07
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Computation of pharmacokinetics parameters by improve simplex method

QIU Di-hua,Zhang Heng,QIU Wei,QUAN Da-yong(School of Chemical Engineering and Pharmacy,Wuhan Institute of Technology,Wuhan 430074,China)  
An improved simplex method is introduced in this paper.The linear and nonlinear pharmacokinetics parameters in various route of administration are computed using the improved simplex method of objective function.And the Delphi computer program for computing the pharmacokinetic parameters is obtained.It is proved by examples that the program has good fitting approximation and is widely applied.
【CateGory Index】: R969.1
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