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《Chinese Journal of Gastroenterology》 2001-04
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Effect of Oxymatrine on Dextran Sulfate Sodium-induced Colitis: A Preliminary Study

ZHENG Ping, NIU Fengli, PENG Yanshen, ZENG Minde. Shanghai Second Medical University Renji Hospital, Shanghai Institute of Digestive Disease, Shanghai (200001)  
Background/Aims: To investigate the effect of oxymatrine (OM) on the experimental murine co- litis. Methods: The colitis was induced by dextran sulfate sodium (DSS) in rats, and the disease activity index (DAI) and pathologic scores were compared among DSS+OM, DSS and control groups, respectively. Results: There were significant differences in the two indices among these three groups (P0.05). Conclusions: OM can ameliorate the symptoms and mucosal damages of DSS-induced colitis in rats.
【CateGory Index】: R574.62
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