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《World Latest Medicine Information》 2015-32
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Efficacy of Combined Therapy of Sitagliptin Phosphate and Metformin for Incipient Type-2 Diabetes Mellitus

Zhang Jie;The department of endocrinology,The first hospital of Huhhot;  
Objective:To analyze the effect of combined therapy of Sitaliptin Phosphate and Metformin for the treatment of patients with incipient type-2 diabetes mellitus(T2DM). M e t h o d s : The clinical data of 70 patients with T2 DM treated in our hospital between February 2013 and February 2015 were retrospectively analyzed. The patients were randomly divided into two groups, an observation group and a control group, each with 35 cases. Patients in the control group was treated with Metformin only, yet those in the observation group were treated with the combined therapy of Sitaliptin Phosphate and Metformin. The efficacy of the two groups was observed.. R e s u l t s : The levels of Hb A1 c, PG and FBG two hours after dinner, in observation group were lower than those in the control group, and its homeostasis model assessment of insulin resistance(HOMA-IR) was better than the control group(P0.05). C o n c l u s i o n : The combined therapy of Sitaliptin Phosphate and Metformin is with significant curative effect for the treatment of T2 DM, which can improve the blood glucose level and HOMA-IR.
【CateGory Index】: R587.1
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