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《Microbiology》 2007-03
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Advance in Studies on Virulence Genes of Vibrio anguillarum

GE Lei 1,2 HUANG Jie 2 LI Qi 1(Key Lab of Mariculture Ministry of Education,Ocean University of China,Qingdao 266003)1(Key Lab for Sustainable Utilization of Marine Fisheries Resource,Ministry of Agriculture Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Science,Qingdao 266071)2  
Vibriosis is fish disease responsible for considerable economic hardship to mariculture operation worldwide.Vibrio anguillarum is an important infectious agent.The first step of infection requires attachment of the bacterium to the host.The flagellum has been suggested to be involved in virulence as a motility organelle that carries an adhesive component.The iron-uptake system of v.anguillarum is important to the pathogenic process.Extracellular compounds such as hemolysin and metalloprotease have been involved in virulence too.The article reviews all factors including exotoxin,adherence factors,invasion factors,cell surface components and iron-uptake system.
【Fund】: 农业部948项目资助(No.2005-Z50)
【CateGory Index】: S941
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