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《Microbiology》 2008-10
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Kinetic Analysis of the Inhibition of in vitro Growth of Pathogenic Escherichia coli K88 and O138 by Lactobacillus Isolates from Porcine Intestine

LIN Yong YAO Wen ZHU Wei-Yun (Laboratory of Gastrointestinal Microbiology, Nanjing Agricultural University, Nanjing 210095)  
Fermentation property and kinetic analysis of the inhibition of in vitro growth of pathogenic Escherichia coli K88, O138 by Lactobacillus intestinalis isolated from porcine intestine mucus were investi-gated. The results of fermentation showed that L1 result in a pH of 3.90 within 12 h and a large amount of lactic acid production, with the concentration of 104.08 mmol/L. Kinetic analysis of the antibacterial activity of L1 metabolic product toward K88, O138 showed that CFUS display strong antibacterial activity toward K88, O138; the antibacterial activity of L1 CFUS was higher than the lactic acid control samples and was mainly due to the production of lactic acid; K88, O138 had the tolerance property toward pH 4.5.
【Fund】: 高校博士学科点专项科研基金(仔猪水肿病的专用疫苗及其益生菌开发的研究)
【CateGory Index】: Q93
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7 LIU Yu-jie;LIU Jun-hua;XU Ting-ting;ZHU Wei-yun;MAO Sheng-yong;The College of Animal Science and Technology,Nanjing Agricultural University;;The effect of glutamine supplementation on the barrier function of ruminal epithelium during high grain diet feeding in dairy goats[J];草业学报;2014-04
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