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ANTIBACTERIAL ACTIVITY ON SKIN AND CHEMICAL COMPOSITION OF THE VOLATILE OILS FROM Agastache rugosa AND Pogostemon cablin

Yang Depo; et al.(Dept. Pharmacy, School of Life Sciences,Univ. of Zhongshan, Guangzhou 510275 )  
The activity of four voatile Oils extracted from Agastache rugoa and Pogostemon cablin was evaluated in vi tro against 16 strains of skin bacteria. Among these oils, Chinese patchouli oil was the most efficacious, it could totally inhibit the growth of almost utilized bacteria with a MIC inferior to 400μl/L, particLdarly causative species of axillary and foot odor. The oil of A. rugosa had a poor inhibition. By means of GS - MS technique, in the oil of A. rugosa, menthone derivatives were identified with the chief compounds. Fo PatchouLli oils, they are: Patchouli alcohol, α - bulnesene and patchoulene. The gdri antibacterial activity of Chinese Patchouli oil could be linked to a high percentage of its main constituents.
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