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《Journal of Hygiene Research》 2001-01
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Effects of conjugated linoleic acid on the metastasis of mouse melanoma B16-MB

Xue Yingben,Chen Bingqing,Zheng Yumei, Yuan Lili,et al. The Public Health School of Harbin Medical University,Harbin 150001,China  
In order to explore the effects of conjugated linoleic acid on tumor metastasis, the proliferation, gap junction intercellular communication(GJIC), adhesion to extracellular matrix, and metastasis cascades of tumor cells were imitated in cell culture. The results showed that 100 and 200μmol/L conjugated linoleic acid could inhibit the proliferation and the adhesion of tumor cells to extracellular matrix,and could recover its gap junction intercellulor communication.
【Key Words】: conjugated linoleic acid metastasis B16 MB melanoma<
【Fund】: 国家自然科学基金!资助项目 (No.30 0 70 6 5 8)
【CateGory Index】: R739.5
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