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《Journal of Hygiene Research》 2006-05
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Effects of formaldehyde on the activity of superoxide dismutases and glutathione peroxidase and the concentration of malondialdehyde

Chang Jun-rui,Xu Dong-qunInstitute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention, Beijing 100021, China  
This review focus on the effects of formaldehyde on the activity of superoxide dismutases (SOD), glutathione peroxidase (GSH-Px) and the concentration of malondialdehyde(MDA) in recent years. It is showed formaldehyde having effect on lipideroxidation by many studies of animal experiment and occupational group, it can decrease the activity of SOD and GSH-Px, increase the concentration of MDA, there are dose-response relationship between those lipideroxidation index and the concentration of formaldehyde too. In future study, the animal experiment and the people's late effect of low dose formaldehyde exposure should be pay more attention.
【Fund】: 科技部社会公益基金重点项目(No.2002DIA10007)
【CateGory Index】: R363
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