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《Journal of Wuhan Institute of Physical Education》 2010-08
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Effects of passive movement and Xiangdan injection on bone mineral density and bone metabolic markers in denevated rats

GAO Li1,LI Xiang-dong2,ZHENG Lu3,et al (1.Dept. of Basic Theory,Shandong Inst. of P.E.,Jinan 250102,China; 2. Clinical Lab,Qianfoshan Hospital,Jinan 250014,China;3. Capital Inst. of P.E.,Beijing 100088,China)  
The purpose of this study was to observe the effects of passive movement and Xiangdan injection on bone mineral density and bone metabolic markers in denervated rats,and to explore their rehabiliation role to discuse osteoporosis. Three-month-old male Wistar rats were randomly divided into sham operation group,simply denervated group,denervated + passive movement group and denervated + Xiangdan group. In addition to the sham operation goup,the other groups were cut off the left sciatic nerve and the femoral nerve,then thirty-day passive movement in passive movement group,and Xiangdan injection gavage in Xiangdan groups. The left femur and tibia bone weight,bone density,serum calcium,alkaline phosphatase,osteocalcin,and tartrate-resistant acid phosphatase 5b concentration were determined. Compared with the sham-operated group,the weight of the tibia and bone mineral density in femur and tibia were significantly decreased in simply denervated group,tartrate-resistant acid phosphatase 5b levels were significantly increased in simply denervated group. Compared with simply denervated group,distal tibial trabecular bone mineral significanlty increased in denervated + Xiangdan groups,alkaline phosphatase and osteocalcin levels significantly increased in denervated + passive movement group and denervated + Xiangdan groups. It could be concluded that the bone mineral density reduced in denervated rats caused by increased bone resorption,passive movement and Xiangdan injection could promote the bone formation and decrease denervated bone density. Xiangdan injection increased bone mineral density better than passive movement.
【Fund】: 北京市市属市管高校北京市重点实验室开放研究课题资助(2007-12)
【CateGory Index】: G804.2
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【Citations】
Chinese Journal Full-text Database 5 Hits
1 LI Jun-han1,HUANG Lei2(1.Department of Sports and Fitness Health,Mianyang Teachers' College,Mianyang 621000,Sichuan,China;2.Dept.of Graduate,Chengdu Institute of Physical Education,Chengdu 610041,Sichuan,China);Biomechanic performance in rats with nerves cutted influenced by passive movement and electricity stimulation[J];山东体育学院学报;2007-03
2 LIU Guo-xiong~1,XIAO Liu-bin~1,ZOU Li-yi~2(1.Longhua People's Hospital,Shenzhen 518109,Guangdong,China;2.Guangdong Medical College,Zhanjiang 524023,Guangdong,China);Study of compound Danshen restraining sclerotin loss in glucocorticoid rats[J];现代中西医结合杂志;2006-23
3 MA Xue-jun (Department of Physical Education, Qufu Teachers Univ., Qufu 273165, Shandong, China);The effects of passive movement and electrical stimulation on the IGF-1, BAKP and TRAP concentration of denervated rats bone[J];山东大学学报(理学版);2005-04
4 GAO Run,ZHANG Su-zhen,LIU Ji-lin,et al.Department of rehabilitation,affiliated Nanjing brain hospital,Nanjing Medical University,Nanjing 210029;Experiment study on the changes of bone mass in denervated rats[J];河南实用神经疾病杂志;2003-06
5 Li Ming,et al. Changhai Hospital,Shanghai;Prevention of Osteoporosis by Medium Frequency Current[J];中华理疗杂志;1991-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Zeng Gao-feng1,Zhang Zhi-yong1,Lu Li1,Xiao De-qiang1,Zong Shao-hui2 1Public Health School of Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China;2Department of Spinal Surgery,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China;Effect and mechanism of polysaccharide intervention in a rat model of osteoporosis[J];中国组织工程研究;2012-50
2 Zheng Jian-fu1, Ding Pi-fan2 1 Zhejiang Police College, Hangzhou 310053, Zhejiang Province, China;2 Chengdu Sport University, Chengdu 610041, Sichuan Province, China;Passive movement and electrical stimulation improve the expression of nerve growth factor in a rat model of disuse osteoporosis[J];中国组织工程研究;2012-37
3 SONG Yawei,ZHANG Xiyuan Author's address Department of Sport and Health Science,Nanjing Institute of Physical Education,Nanjing,210014;The influence of different load trainings of different length of time on compression properties of rabbit femur[J];中国康复医学杂志;2011-08
4 WANG Xuehong,ZHOU Baojun(Wuhan Sports University,Wuhan 430079,Hubei);Establishing animal model of fracture after osteoporosis[J];湖北中医学院学报;2010-06
5 LI Jun-han,et al (Department of Sports and Health Education,Mianyang Normal University);The influence of passive movement and electric stimulation on the bone BGP and TRACP in rats with denervation[J];重庆医科大学学报;2010-08
6 GAO Li1,LI Xiang-dong2,ZHENG Lu3,et al (1.Dept. of Basic Theory,Shandong Inst. of P.E.,Jinan 250102,China; 2. Clinical Lab,Qianfoshan Hospital,Jinan 250014,China;3. Capital Inst. of P.E.,Beijing 100088,China);Effects of passive movement and Xiangdan injection on bone mineral density and bone metabolic markers in denevated rats[J];武汉体育学院学报;2010-08
7 YANG Xueping,CHEN Jun,LU Li,et al. The Center of New Drug Function,School of Life Science and Biopharmacy,Guangzhou 510006,China;The different effects of short-term application of glucocorticoids in cancellous and cortical bone in SD rat[J];中国骨质疏松杂志;2010-04
8 SUN Lian-Wen XIE Tian FAN Yu-Bo(School of Biological Science and Medical Engineering,Beihang University,Beijing 100191);Application of Exercise and Effect on Musculoskeletal System in Tail-suspension Rats[J];中国生物医学工程学报;2009-05
9 Su Hua, Wu Tie, Zhao HuaDepartment of Pharmacology, Guangdong Medical College, Zhanjiang 524023, Guangdong Province, China;Effects of Shuangshen oral liquid on glucocorticoid-induced osteoporosis rats[J];中国组织工程研究与临床康复;2009-41
10 WANG Li-tong~1,ZHAN Hong-sheng~2 1.TianShan Hospital of Traditional Chinese Medicine,ChangNing District,Shanghai 200051;2.ShuGuang Hospital, affiliated to Shanghai University of Traditional Chinese Medicine,200021;Duplication of animal model with secondary osteoporosis and its mechanism[J];中华骨质疏松和骨矿盐疾病杂志;2009-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 MA Xue-jun (Department of Physical Education, Qufu Teachers Univ., Qufu 273165, Shandong, China);The effects of passive movement and electrical stimulation on the IGF-1, BAKP and TRAP concentration of denervated rats bone[J];山东大学学报(理学版);2005-04
2 Pan Xiao gui,Gao RunPan Xiao gui,Department of Physical Education,West Anhui University,Liu'an 237012,Anhui Province,ChinaGao Run,Department of Rehabilitation Medicine,Nanjing Brain Hospital,Nanjing 210024,Jiangsu Province,China;Changes of trabecular bone microarchitecture in denervated rats and reversion effects of passive movement[J];中国临床康复;2005-04
3 LI Chang-hong*, WU Qian. *463 Hospital of PLA, Shenyang 110042, China;The effects of passive movement and electrical stimulation on soleus of the rats treated with tail suspension[J];中华物理医学与康复杂志;2004-03
4 YANG Guomin (Graduate Department Shanghai Institute of P.E. Shanghai 200438);Change of Bone Mineral Density and Biomechanics Influences by Exercise and Low Frequency Pulsing Electromagnetic Fields Ovariectomized Rats[J];成都体育学院学报;2004-01
5 GAO Run,ZHANG Su-zhen,LIU Ji-lin,et al.Department of rehabilitation,affiliated Nanjing brain hospital,Nanjing Medical University,Nanjing 210029;Experiment study on the changes of bone mass in denervated rats[J];河南实用神经疾病杂志;2003-06
6 MA Hui-ping 1,JIA Zheng-ping 1,GE Xin 1,HE Xiao-ying 1,CHEN Ke-ming 2,BAI Meng-hai 2 1.Department of Pharmacy, Lanzhou General Hospital, PLA, Lanzhou 730050,China 2.Institute of Orthopaedics, Lanzhou General Hospital, PLA, Lanzhou 730050,China;STUDIES ON THE THERAPUTIC EFFECT OF TOTAL FLAVONOIDS OF HERBA EPIMEDII ON EXPERIMENTAL OSTEOPOROSIS IN RATS[J];华西药学杂志;2002-03
7 MA Tao, CUI Liao, WU Tie, et al.Department of Pharmacology,Guangdong Medical College, Zhanjiang\ 524023,China;Effects of serum of aged male rat treated with epimedium herb extract on proliferation and differentation of rat calvarium osteoblast in vitro[J];中国骨质疏松杂志;2002-01
8 XIANG Qun,WANG Xian ping,SUN Wenmin,et al.Yancheng First People's Hospital,Yancheng 224001,China;Interventional treatment of pulsed electromagnetic fields(PEMFs) on senile osteoporosis[J];中国临床康复;2002-03
9 KE Li,CHEN Lulu,TU Yihui,et al.Wuhan Fourth Hospital,Wuhan 430033,China;Effect of pulsing electromagnetic fields on prevention of osteoporosis in ovariectomized rats[J];中国骨质疏松杂志;2001-03
10 ZUO Yong chang1, ZHU Yu zhen2, LI Wen3, HE Shi peng4, DING Gui feng5(1 Department of Immunology,Jinggangshan Medical School,Jian,Jiangxi 343000) (2 Baoji Health School,Baoji,Shangxi 721000;3 Jiangxi Medical college,Nanchang;Effect of restraint stress on levels of serum insulin like growth factor-I[J];井冈山医专学报;2000-03
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