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Correlation of Lead Levels in 3-Month Old Infant Blood,in Maternal Blood and Breast Milk in Jiangmen City,Guangdong Province

ZHANG Li-fan,GUO Xiao-fang,FANG Wen,WU Xun,LI Qing-fu(Jiangmen city xinhui district women and children health hospital,Jiangmen 529100,China)  
Objective:To understand the correlation of blood lead levels in 3-month old infant,in maternal blood and breast milk and to explore the high risk factor effecting blood levels of infant.Method: A cross-sectional descriptive study was carried out among normal 3-month old infant with exclusive lactation or partial lactation born in Maternal and Child Health,Xinhui District,Jiangmen City,Guangdong Province from January to March April,2005.The lead levels of infant blood,maternal blood and breast milk were measured respectively and the related factors influencing infant blood lead levels were analyzed. Result: No significant difference was observed between lead levels in infant blood(49.53±23.6 μg/L) and in cord blood(49.70±23.77 μg/L)(P0.05) which were both lower than that in maternal blood(59.24±28.71 μg/L)(P0.05) but higher than that in breast milk(26.77±13.70 μg/L)(P0.05).Partial correlation analysis showed the blood lead level of 3-month old infant was positively associated with lead levels in cord blood,maternal blood and breast milk respectively(Spearman coefficient of partial correlation=0.39,0.42 and 0.31 respectively,P0.01).The multiple regression analysis showed that after the adjustment of habitation,history of lead contact,sex etc,every increase of breast milk in 1 μg/L unit resulted in the increase of blood lead of infant by 14 μg/L.Conclusion: There were significant effect of lead levels in maternal blood and breast milk on the lead levels in 3-month old infant blood and the quantitative assay and analysis of lead in breast milk was very important for the prevention and cure of the children early exposure to lead.
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