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《Journal of Wenzhou Medical College》 2001-01
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Study of the antioxidant defense system in the kidney of diabetic rats

NI Lian song,WU Wan ling,SHENG Hong guang, et al. Department of Endocrinology, 1st Affiliated Hospital, Wenzhou Medical College, Wenzhou, 325000  
Objective:To study the effect of diabetes on renal antioxidant defense function.Methods:The levels of malondialdehyde (MDA), glutathione (GSH), and the activities of antioxidant enzymes viz., [superoxide dismutase (SOD), glutathione peroxidase (GSH PX), glutathione s transferase (GSH ST) and catalase (CAT)] were investigated in the renal cortex of diabetic rats at 12th week.Results:The activities of SOD, GSH-ST and CAT were significantly lower in the diabetic group than normal one. The level of GSH was decreased too, MDA showed no change, whereas GSH PX activity of the diabetic group was theincreased.Conclusion:The antioxidant defense function in the kidney of diabetic rats decreased obviously.
【CateGory Index】: R587.1
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1 LI Xiao mei,LU Yan juan,LI Xiao lin * (Experimental Center of Biochemistry and Molecular Biology,School of Basic Medical Sciences, Jilin University, Changchun 130021,China);Changes of POD activities in the key organs in adult rats with diabetes[J];Journal of Jilin University of (Medicine Edition);2004-01
2 LU Yan juan, LI Xiao lin , LI Xiao mei (Experimental Center of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Jilin University, Changchun 130021,China);Changes of levels of GSH-Px, GSH,and GR in important organs and tissues of adult diabetic rats[J];Journal of Jilin University of (Medicine Edition);2004-03
3 WANG Cui-Zhen, LIN Li-Xiang, CHEN Gang, et al (Fujian Medical University, Clinical Institute of Fujian Provincial Hospital, Fuzhou 350001, China);The Expression of Oxidative Stress Related Genes in Kidney Tissue of Type 2 Diabetic Rats[J];Strait Journal of Preventive Medicine;2005-02
4 SU Ning1,LUO Rongjing1,SU Hang2,LUO Hui1,LANG Jianying1,NONG Hui1,LI Li1 (1.Basic Medical College,Guangzhou University of TCM,Guangzhou 510006;2. Dept. of Clinical Molecular Medicine,the Second Affiliated Hospital of Guangzhou Medical College,Guangzhou 510260);Effect of Baicalin on Renal Function in Diabetic Nephropathy Rats and Its Anti-oxidative Action[J];Traditional Chinese Drug Research & Clinical Pharmacology;2007-05
Chinese Journal Full-text Database 7 Hits
1 WANG Bai-xin1,ZHANG Fu2,LU Ya-zhen1,ZHANG Jian-hua1, LI Kai-xia1 (1.Basic Medical College of Jiamusi University, Jiamusi 154002, China;2.The Second Hospital of Mining Industry Group of Shuang yashan,Shuangyashan 155100, China);Antioxidant defense system in the kidney of diabetic rats[J];Heilongjiang Medicine and Pharmacy;2004-03
2 BAO Bei_yan,SHEN Han_chao.Department of Nephrology,Yinzhou People′s Hospital of Ningbo City,Ningbo 315040,China;Change of glutathione anti-oxidation system in diabetic nephropathy at early stage[J];Journal of Postgraduates of Medicine;2005-03
3 WANG Fang~1,CHEN Xiao-fei~2,CHEN Guo-rong~1,LI Xu-sheng~1,LEI Kang-fu~3,MAO Sun-zhong~3(~1 Department of Pathology,~2 Department of Clinical Laboratory, The First Affiliated Hospital,~3 Department of Biochemistry,Wenzhou Medical College,Wenzhou 325027,China);Effects of extract of gingko biloba on the lipid metabolism and the function of macrophages from diabetic rats[J];Chinese Journal of Pathophysiology;2006-10
4 Loren E WOLD~1, Asli F CEYLAN-ISIK~2, Jun REN~(1,2,3) ~1 Department of Pharmacology, Physiology and Therapeutics, University of North Dakota, Grand Forks, ND 58203, USA; ~2 Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, WY 82071, USA;Oxidative stress and stress signaling: menace of diabetic cardiomyopathy[J];中国药理学报(英文版);2005-08
5 XUE Hua1,QIAO Jin1,MENG Guoliang1,WU Feng1,LUO Jia1,CHEN Hui2,ZHENG Huihua2,XU Jiliang1 (1.Department of Pharmacology,Medical College,Nantong University,Nantong 226001,China; 2. Jiangsu Alphay Biological Technology Co. Ltd.,Nantong 226006,China);Effect of Ganoderma lucidum polysaccharides on hemodynamic and antioxidation in T2DM rats[J];China Journal of Chinese Materia Medica;2010-03
6 Mustafa Cemek, Department of Chemistry (Biochemistry Division), Faculty of Science, Afyon Kocatepe University, Afyon, Turkey Semiha Dede, Nihat Mert, Department of Biochemistry, Faculty of Veterinary Medicine, Yznc Y1l University, Van, Turkey Fahri Bayiro■lu, Department of Physiology, Faculty of Veterinary Medicine, Yznc Y1l University, Van, Turkey Hseyin ■aksen, Fatma Cemek, Department of Pediatrics, Faculty of Medicine, Yznc Y1l University, Van, Turkey;Relationship between antioxidant capacity and oxidative stress in children with acute hepatitis A[J];世界胃肠病学杂志(英文版);2006-38
7 A Shirpoor,F Ghaderi Pakdel,Department of Physiology,Faculty of Medicine,Jaddeh Nazloo,Urmia,Iran MH Khadem Ansari,S Salami,Y Rasmi,Department of Biochemistry,Faculty of Medicine,Jaddeh Nazloo,Urmia,Iran;Effect of vitamin E on oxidative stress status in small intestine of diabetic rat[J];世界胃肠病学杂志(英文版);2007-32
Chinese Journal Full-text Database 10 Hits
1 Wang Xianyuan Gao Lanxing (Institute of Hygiene and Environmental Medicine, Academy of Military Medical sciences, Tianjin 300050);Research progress on antivirus of MAP30 from Moomordica charantia[J];AMINO ACIDS & BIOTIC RESOURCES;2000-02
2 WANG Xian-yuan, JIN Hong, XU Zhi-qin, GAO Lan-xing (Institute of hygiene and environmental medicine, Academy of military and medical sciences, 300050 Tianjin);Study on Hypoglycemic Effect of Momordica saponins and Its Mechanism[J];Amino Acids & Biotic Resources;2001-03
3 Wang Zhongshan,Wang Hongjun,Xu Zongge,Zuo Wenjing (Dept.of Cell Biology,School of Basic Medical Sciences)〔;Comparison of cellular enzyme activities of heart,liver,kidney and serum in puberty rats with diabetes[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;2000-04
4 Zhang Jiaying1,Wang Zhongshan2,Zuo Wenjing2,Xu Zongge,2Wang Chengzhong2(1\ Dept.of Molecular Biology;2\ Lab.of Cell Biology,School of Basic Medical Sciences)w;Analysis of serum biochemistry compositionsin puberty rats with diabetes[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1998-03
5 WANG Hai song, XIE Chun guang(王海松,等) Chengdu University of TCM (Chengdu, 610075,China);Effect of Yi-sheng-tang-tai Granula to the Nephritic Pathological Changes of the Diabetic Rats[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;2000-01
6 ZHANG Chuan Sen 1, JIANG Zong Lai 1, CHEN Er Yu 1, XU Rui Sheng 1, YANG Xiang Qun 1, QUAN Shan Cong 2, ZHANG Wei Dong 3 (1.Department of Anatomy, Department of Basic Medicine, Second Military Medical University, Shanghai 200433, China; 2.De;Effect of CPI on remodeling of renal vessels in diabetic rats[J];Academic Journal of Second Military Medical University;2000-06
7 MEI Xiao Bin 1* , YUAN Wei Jie 1, GAO Cong Rong 2, CHEN Yan Feng 3, LU Jun 1, LI Bao Chun 1, YU Jian Ping 1, CUI Ruo Lan 1 (1. Department of Nephrology, Changhai Hospital, Second Military Medical University, Shanghai 200433,China;2. Department of Endocrinology, Changhai Hospital;3.Hygenic Group,No. 77625 Troop of PLA, Lhasa 851400);Effect of low-protein diet on renal hypertrophy of diabetic glomerulus and its relationship with cyclin kinase inhibitor P27 level[J];Academic Journal of Second Military Medical University;2003-08
8 ;Evaluation of methods to detect insulin resistance in vivo[J];Acta Academiae Medicinae Militaris Tertiae;2004-03
9 LI Zhen Jiang 1, LEI Jie 2, ZHONG Fang Hong 3, CHEN Wei 1 1Department of Renal Diseases, Xijing Hospital, Fourth Military Medical University, Xian 710033, China, 2Department of Endocrinal & Renal Diseases, Xian Central Hospital, Xian 710003, 3Xian Thoracic Cancer Hospital, Xian 710061, China;Clinical significance of level changes of TGF-β_1 and IV collagens and therapeutic effects of simvastatin in patients with diabetic nephropathy[J];Journal of The Fourth Military Medical University;2004-10
10 Bai Quan , Ge Xiaojuan, Geng Xindu (Institute of Modern Separation Science, Key Laboratory of Modern Separation Science in Shaanxi Province, Northwest University, Xi′an 710069);The Purification of Peptide in Preparative Scale with Reversed Phase High Performance Liquid Chromatography[J];Chinese Journal of Analytieal Chemistry;2002-09
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 DONG Zhi-heng 1△,LI Cai 1,QU Meng2 (1.Department of Pathology,Institute of Frontier Medical Sciences,Jilin University, Changchun 130021,China;2. Department of Molecular Biology, College of Medical Sciences,Beihua University,Jilin 132001,China);Effects of benazepril on CTGF in myocardium of diabetic rats and its mechanism[J];Journal of Jilin University of (Medicine Edition);2004-04
2 YANG Li-na~1,LI Hong-yan~1,LIU Ya-wen~2,SHI Jie-ping~2,LIU Qing~3,LI Dan-yang~1,QIAO Hui-zhen~2,LIU Ya~(1)(1.Department of Nutrition and Food Hygiene,School of Public Health,Jilin University,Changchun 130021,China;2.Department of Epidemiology,School of Public Health,Jilin University,Changchun 130021,China;3.Department of Endocrinology,First Hospital,Jilin University,Changchun 130021,China);Association between MT2A gene polymorphism and type 2 diabetes mellitus[J];Journal of Jilin University of (Medicine Edition);2005-05
3 HUANG Min,YUAN Hai-bo, SHI Yi~△,WANG Shao, YANG Wei (Department of Physiology, School of Basic Medical Sciences,Jilin University, Changchun 130021, China);Effect of Biondia Heriyi extract on blood glucose level in Streptozocin-induced diabetic rats[J];Journal of Jilin University(Medicine Edition);2006-05
4 CHENG Fa-feng1,SONG Wen-ting2,GUO Shao-ying1,ZHONG Xiang-gen1,LU Yi1,WANG Qing-guo1(1School of Preclinical Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;2Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China);Protective effect of baicalin on H_2O_2 injured rats' primary cortical neurons[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-05
5 ;白藜芦醇对高糖环境近端小管上皮细胞氧化应激的影响[J];Contemporary Medicine;2011-02
6 SUI Yan,LI Wei,YANG Yun-fen,XU Xiu-dong,LI Wen-fang Medical College,Wuhan University of Science and Technology,Wuhan 430065,China;Study on the protective effect of baicalin on oxidation damage in A549 cell[J];Journal of Public Health and Preventive Medicine;2012-02
7 Su NingZhao Ping She Yan-ling Zhou Le-quan Du Biao-yan Luo Hui Lang Jian-ying School of Basical Science,Guangzhou University of TCM,Guangzhou China 510006;Study on Effects of Baicalin Bai on the Repaired of Injured Podocytes in Diabetic Nephropathy Rats[J];China Journal of Chinese Medicine;2011-07
8 SU Ning,LI Feng,ZHAO Ping,ZHOU Le-quan,KUANG Zao-yuan,DU Biao-yan,LUO Rong-jing (Basic Medical College,Guangzhou University of Traditional Chinese Medicine,Guangzhou Guangdong 510006);Experimental Study of Baicalin on Regulation of Local Bioactive Substances in Kidney of DN Rat[J];World Journal of Integrated Traditional and Western Medicine;2010-01
9 LI Chuan,ZHU Ke-xue,NIE Shao-ping,HU Xiao-bo,HUANG Dan-fei,XIE Ming-yong (State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047,China);Protective Effect of Zinc Threonine against Liver Injury in Diabetic Rats[J];Food Science;2011-19
10 GUO Shao-ying1,CHENG Fa-feng1,ZHONG Xiang-gen1,LU Yi1,SONG Wen-ting2,WANG Qing-guo1(1.School of Preclinical Medicine,Beijing University of Chinese Medicine,Beijing,100029,China;2.Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091,China);Antioxidative Effects of Baicalin in vitro[J];Lishizhen Medicine and Materia Medica Research;2011-01
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