EFFECT OF EPIMEDIUM FLAVONE TOTAL (EFT) ON CELLULAR AND ERYTHROCYTIC IMMUNOFUNCTION OF EHRLICH ASCITES CANCER(EAC) BEARING MICE
Hao Binghua,Tao Ming, He Liduan et al (Department of Publi Health Microbiology and Immunology, Faculty of Preventive Medicine)
We studied effect of Epimedium Flavone Total(EFT) on the immunofunction of mice was burdened with Ehrlich Ascites Cancer (EAC) ,and tested the lymphocyte transformation rate, erythrocyto C 3b receptor rossette rate,erythrocyto immunocomplexs rossette rate,phagocytosis of macrophagocyte in peritoneal cavity. The results showed that EFT could increase phagocytosis activity of macrophagocyte (P0 05),promote lymphocyte transformation rate (P0.05) and increase the sero antibody level meanly (P0.05),while low dosage group could increase Plaque Forming Cell( PFC) significantly (P0.05),raise the ratio value of spleen to body(P0.05) of EAC bearing mice.So we say that EFT might be enhance burdened mice′s immunofunction. Lowdosage could improve sero antibody level.Effect on regulating cellular immunofunction are related to dosage.EFT may be inhibit the growth of EAC cells to some degree.