Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Medical Research and Education》 2010-06
Add to Favorite Get Latest Update

The Expression of glutathiones transferases-π in the tissue of bladder carcinoma

Qi Lili1,Wei Ruojing1,Fu Weijun2,et al.(1.Department of Urology,the Affiliated Hospital of Heibei University,Baoding 071000,China;2.Department of Urology,General Hospital of PLA,Beijing,100853,China)  
Objective To study the relationship between glutathiones transferasesπ(GST-π) expression in bladder cancer and biological behavior.Methods 147 samples of bladder cancer were determined with immunohistochemistry for the expression of GST-π.Results The expression rate of GST-π was 52.4%(77/147).In the 68 cases with grade Ⅰ the expression rate was 39.7%(27/68);in 49 cases with grade Ⅱ the expression rate was 57.1%(28/49);in 30 cases with grade Ⅲ the expression rate was 73.3%(22/30),in 117 cases with primary bladder cancer the positive expression rate was 57.3%(67/117),in 30 cases with hydroxycamptothecin intravesical recurrence of bladder cancer chemotherapy the positive expression rate was 96.7%(29/30).The results show that the level of GST-π expression in bladder cancer,malignant behavior were closely related to pathological grade(P0.05).Conclusion The results show that the expression of GST-π could reveal the unsuccessful intravesical themotherapy.The expression of GST-π has correlation with the malignant degree and the pathological gradingof bladder cancer.
【CateGory Index】: R737.14
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 2 Hits
1 ZHAO Huan-fen, ZHANG Yong-mei, HE Chun-nian, SONG Guang-yao, ZHAI Jin-ping Hebei General Hospital, Shijiazhuang 050051, P.R.China;Relation between tumor drug resistance and expression of hypoxia induced factor 1α in lung carcinoma[J];Chinese Journal of Cancer Prevention and Treatment;2008-07
2 LI Zhishan,ZHANG Rugang, LUO Xianmao,et al. Department of Thoracic Surgery,Cancer Institute(Hospital),Chinese Academy of Medical Sciences, Peking Union Medical College,Beijing 100021, China;Expression of glutathione S-transferase-π in human esophageal squamous cell carcinoma[J];Chinese Journal of Oncology;2001-01
Chinese Journal Full-text Database 10 Hits
1 YU Long,HU Hai,RAN Yu-Liang,PENG Liang-Ping,LI Jiang-Wei,YANG Zhi-Hua Department of Cellular and Molecular Biology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing,100021, P.R.China;Human Esophageal Carcinoma Antigens Screened by Serologic Analysis of Recombinant cDNA Expression Libraries(SEREX)[J];Chinese Journal of Cancer;2007-01
2 Wang Wentao1,Liu Hongbin2(1.Department of Radiology,the Third People's Hospital of Rudong,Rudong 226406,China;2.Department of Patholog,the Second Affiliated Hospital of Nantong University,Nantong 226001,China);The Expression and Significance of GST-π in Different Area of Esophageal Diseases[J];Journal of Basic and Clinical Oncology;2007-06
3 YANG Yingtao 1) , LIU Linbo 2) , LI Hongzhe 3) 1)Department of Plastic Surgery, the Second Affiliated Hospital, Zhengzhou University, Zhengzhou 450014 2)Department of Plastic Surgery, the First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052 3)Central Hospital of Yima Coal Corporation, Yima 472300;Expression of glutathione S-transferase π and multi-drug resistance associated protein in squamous cell carcinoma tissue[J];Journal of Zhengzhou University(Medical Sciences);2006-06
4 LI Juan,LIU Hongbin1(The Wenfeng Hospital of Nantong, Jiangsu 226001;1The Second Affiliated Hospital of Nantong University);The study of expression and significance of Cyclin D1 and GST-π in different esophageal diseases[J];Medical Journal of Communications;2008-06
5 KANG Xin-Li, GENG Zhen-Hong, LU Xin-Xiang, WEI Chao, WANG Jin-Gang, WANG San-Zhong, MA Sen, LIU Hong- Xin, XU Guo-Ying, ZHANG Hua-Wei, WANG Guo-Yong. ( Department of Urology, Shengli Hospital, Dongyine 257055, Shandong Province, China.);Evaluating the effect of intravesical chemotherapy by expressions of P-gp, GST-π and TOPO- Ⅱ in bladder cancer tissues[J];Journal of Modern Urology;2003-03
6 CHANG Xin zhong,DING Yin lu,WANG Zhan min.Department of General Surgery,Qilu Hospital of Shandong University,Jinan 250012,China;Expression of MRP and GST-π in Pancreatic Carcinoma and Its Clinical Significance[J];Journal of Qilu Oncology;2002-04
7 FENG Dan, LIU Yun-peng Department of Medical Oncology,First Affiliated Hospital of China Medical University, Shenyang 110001,P.R.China;Research progress of GST-π and multidrug resistance in malignant neoplasm[J];Journal of Qilu Oncology;2004-06
8 DU Jing1,ZHAO Qiu21.Department of Gastroenterology,Zhejiang Provincial People's Hospital,Hangzhou 310014,P.R.China2.Department of Gastroenterology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,P.R.China;Inhibitory effect of YC-1 on stability and transcriptional activity of HIF-1 in hypoxic human liver cancer cells-HepG-2[J];Chinese Journal of Cancer Prevention and Treatment;2009-05
9 Guo Wei,et al. (Department of Gastroenterology,First Affiliated Hospital of Qiqihar Medical University,Heilongjiang Province 161041,China);Expression of P-glycoprotein and Glutathione(GST-) in Gastric Carcinoma and Its Clinical Significance[J];Journal of Qiqihar Medical College;2007-03
10 TIAN Xue-zhi,FAN Ning-fang,XU Hui-juan(Tumor Hospital of Shanxi Province,Taiyuan 030013,China);Investigation of the activity of multidrug resistance GST in the plasma of breast cancer patients with its clinical significance[J];Proceeding of Clinical Medicine;2009-28
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 ZHANG Yong-mei, WANG Zhao-qing, SUN Jian-suo, SONG Guang-yao Key Geriatric Laboratory, Hebei Provincial General Hospital, Shijiazhuang 050051, P.R.China;Expressions and significance of MRP1 mRNA and GST-π mRNA in NSCLC tissues[J];Chinese Journal of Cancer Prevention and Treatment;2007-12
2 WANG Yong-lai1,LIU Cai-gang2,CHEN Shuang1,HUANG Shuo11.Department of Obstetrics and Genecology,Shengijing Hospital,China Medical University,Shenyang 110004,P.R.China2.Department of Surgical Oncology,First Affiliated Hospital of China Medial University,Shenyang 110001,P.R.China;Effection of HIF-1α and VEGF in tumor angiogenesis of endometrial cancer[J];Chinese Journal of Cancer Prevention and Treatment;2007-15
3 WANG Yan-fen1,DING Yong-ling1,WANG Dong-lin2,SHI Gong-sheng2,ZHOU Xiao-ming1,LI Jia-yu1 1.Department of Pathology,First Hospital of Yangzhou,Yangzhou 225001,P.R.China2.Nantong University,Nantong 226001,P.R.China;Relationship between the expressions of HIF-1α,COX-2 and CD105 in human glioma tissues and clinicopathology[J];Chinese Journal of Cancer Prevention and Treatment;2007-19
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved