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《Acta Agriculturae Boreali-occidentalis Sinica》 1993-01
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PRELIMINARY STUDIES ON THE RELATION OF STRUCTURE —— ACTIVITY OF DIHYDROAGAROFURAN COMPOUNDS

Wu Wenjun Liu Huixia (Department of Plaut Protection, Northwestern Agricultural University Shaanxi Yangling 712100) Tu Yongqiang (Department of Chemistry, Lanzhou University Gans: 730900)  
The studies on the relation of structure-activity of 11 dihydroagarofuran compounds from Celastraceae Plants have been carried out in our laboratory. The results indicated that the hydroxy at C—4 was responsible for the antifeeding activity, that the isobutanoyloxy at C—12 might be an important poisonous active group, moreover, the β configuration was more active than the a configuration for a pair of isomers. The results also showed that the furancarbonyloxy at C—8, C—9 companied by isobutanoyloxy at C—12 might play an important role in narcotic activity.
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