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《Acta Agriculturae Boreali-Occidentalis Sinica》 2009-05
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Age-related Expression of Ghrelin in Small Intestine of Ostrich

ZHOU Xu1,XU Li1,SHI Fangping2 and ZHAO Huiying1(1.College of Veterinary Medicine,Northwest A &F University,Yangling Shaanxi 712100,China;2 Shaanxi Iko Ostriches CO,LTD,Xi'an Shaanxi 710014,China)  
To study the the age-related expression rules of Ghrelin in small intestine of ostrich and the foundation of cytology on regulation of appetite with Ghrelin.The expression and changes of ghrelin-imunopositive(ghrelin-ip) cell were detected with immunohistochemical SP method in Ostrich's small intestine during 3 days,3 weeks and 9~11 months.Results: Ostrich's small intestine of different ages all had ghrelin-ip cell,it was distributed in Mucosal layer of small intestine,there were more ghrelin-ip cells in the intestinal villus and the glands of small intestine than that in other sections of it.Ghrelin-ip cell was columnar cell,endocrine cell,lymphocyte and so on;The expression of ghrelin-ip cell increased with growing.Compared with the 3 weeks of ostrich,the expression of 9~11 months of ostrich increased obviously,and the 3 days of ostrich had the least expression;The expression of Ghrelin-ip cells also was different in duodenum,jejunum and ileum.The duodenum had the most of expression,the ileum had the least of that.The difference of relative expression of ghrelin-ip cell in every intestine during 3 days and 3 weeks was not conspicuous(P0.05),but it during 9~11 months was conspicuous(P0.05).It manifested that the expression of Ghrelin increased with growing.Ghrelin might regulate the development of small intestine through autocine and paracrine.
【Fund】: 陕西省自然科学基金项目(SJ08C105)
【CateGory Index】: S839
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