Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of AIDS & STD》 2008-02
Add to Favorite Get Latest Update

Study on molecular epidemiology of human immunodeficiency virus type 1 infection in men who have sex with men(MSM) in Shenzhen

ZHAO Guanglu,FENG Tie-jian,ZHAO Jin,et al.(Shenzhen Center for Disease Control and Prevention,Shenzhen,Guangdong 518020,China)  
Objective To investigate the molecular epidemiology of human immunodeficiency virus-1(HIV-1)infection among men who have sex with men(MSM)in Shenzhen and to study related risk factors so as to predict the epidemic trend and evolution.Method Eighteen HIV-1 positive sera samples of MSM were collected in 2006.HIV-1 env/gag genes were amplified by nested-PCR from RNA.The C2-V3 region of HIV-1 env and P24 region were sequenced for analyses.Phylogenetic analyses were performed based on the nucleotide sequence data.Results Among 18 samples,there were 4 HIV-1 strains including CRF01-AE,CRF08-BC,CRF07-BC 3 circulating recombinant forms(CRFs)and B 1 subtype.Genotyping showed that 55.56%(10/18)were CRF01-AE,16.67%(3/18)were CRF07-BC,5.56%(1/18)were CRF08-BC and 22.22%(4/18)were subtype B;In Env region,the AE group showed the highest homology to 01AE.TH.90.CM240 strain,with the genetic distances of(8.778±1.296)%,and the inner groups distance of(10.192±4.179)%.The 07-BC group showed homology to 07-bc.cn.97.97cn001 strain,and the genetic distances was(7.650±0.212)%,and the inner groups distance was 2.000%.The 08-BC group showed homology to 08-bc.cn.97.97cngx-9f strain,and the genetic distances was 11.350%,The B group showed homology to B.US.86.JRF strain,the genetic distances was(13.300±0.819)%,and the inner groups distance was(14.376±8.812)%;In gag region,the AE group showed the highest homology to 01AE.TH.90.CM240 strain,and to 07-bc.cn.97.97cn001 strain,and the genetic distances was(2.167±0.551)%,the inner groups distance was(0.700±0.346)%.The 08-BC group showed the highest homology to 08-bc.cn.97.97cngx-9f strain,and the genetic distances was 4.800%;The B group showed the highest homology to B.FR.83.HXB2 strain,the genetic distances was(7.350±1.926)%,and the inner groups distance was(10.167±4.352)%.Conclusion CRF01-AE was the main epidemic CRF strains in MSM population in Shenzhen region,followed by Subtype B and CRF07-BC,and CRF08-BC was also prevalent in them.
【Fund】: 广东省医学科研基金(编号A2005633)
【CateGory Index】: R181.3
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 6 Hits
1 LIU Zhi-ying1,LI Hai-ying2,ZHANG Tong2,HUANG Xiao-jie2,WEI Fei-li1,XU Meng1,JIAO Yan-mei1,XU Xiao-ning2,CHEN De-xi1,WU Hao2(1.HIV/AIDS & STD Laboratory,Beijing Youan Hospital,Capital Medical University;2.Department of Infections Diseases,Beijing Youan Hospital,Capital Medical University);Molecular Epidemiologic Study on Human Immunodeficiency Virus Type 1 Infection in Partial Men Who have Sex with Men(MSM) in Beijing[J];Journal of Capital Medical University;2009-05
2 SHI Xiang-dong,ZHAO Guang-lu,SONG Jun-min,et al.(Shenzhen Municipal Center for Disease Control and Prevention,Shenzhen,Guangdong 518020,China);Study on early laboratory diagnosis of vertical transmission of human immunodeficiency virus type 1 and molecular epidemiology in Shenzhen[J];Chinese Journal of AIDS & STD;2008-06
3 LIU Li-hua,YANG Li-hua,ZHAO Xin-rong,et al.Shijiazhuang Center for Disease Control and Prevention(Shijiazhuang 050011,China);Subtype distribution of HIV-1 among different people infected[J];Chinese Journal of Public Health;2009-08
4 HAN Zhi-gang,XU Hui-fang,LI Yan,et al.(Guangzhou Center for Disease Control and Prevention,Guangzhou,Guangdong 510080,China);Molecular epidemiology of HIV-1 infection among MSM in Guangzhou[J];Chinese Journal of AIDS & STD;2009-04
5 ZHANG Shu,GAO Hong,HU Feng-jiao,NI Hong-xia,JIAO Su-li(Ningbo Center for Disease Control and Prenvention,Ningbo 315010,China);Subtype and sequence analysis of HIV-1epidemic in Ningbo[J];Chinese Journal of Health Laboratory Technology;2009-12
6 HE Qin,ZHANG Xia,SHUAI Jun,et al .(The Department of Dermatology,Futian Hospital,Shenzhen,Guangdong 518033,China);A molecular epidemiological study of HIV-1 transmission among injection drug users and heterosexuals in Shenzhen City[J];Chinese Preventive Medicine;2009-12
【Citations】
Chinese Journal Full-text Database 2 Hits
1 SONG Dan, TAO Xiao - yan, CAI Wen -de, et al. (Central Laboratory of Reproduction of Luohu Hospital of Shenzhen City, Shenzhen 518001, Guangdong, P. R. China);Survey of sexual behavior of male homosexuals and intervention measure for control of AIDS hi Shenzhen City.[J];China Tropical Medicine;2005-04
2 Yao Jun , Zhang Fujie, He Zhangping, et al. Beijing Ditan Hospital, Beijing 100011, P. R . China;Subtype and sequence analysis of the C2-V3 region of env gene among HIV-1 infected homosexual men in Beging[J];Journal for China AIDS/STD;2002-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 HUA Qiudong1,2, JIANG Chenggang2, WANG Hai1, XIANG Wenhua2, ZHOU Jianhua2, CHEN Weiduo1 (1. College of Life Sciences, Northeast Agricultural University, Harbin 150030, China; 2. Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, China);Expression, purification and bioactivity test of SHIV capsid p27[J];Journal of Northeast Agricultural University;2008-11
2 LI Yan, XU Hui-fang, HAN Zhi-gang, et al. Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China;Sequence analysis of the C2-V3 region among HIV-1 strains found during 2004-2005 in Guangzhou[J];South China Journal of Preventive Medicine;2008-01
3 Zhu Hong, et al Beijing Entry - Exit Inspection and Quarantine Bureau;Clinical Evaluation on Several anti - HIV Diagnostic Reagents[J];Chinese Journal of Frontier Health and Quarantine;2001-02
4 ZHANG Bei-chuan,Joan Kaufman (Qingdao University, Qingdao 266012, China);Homosexuality and AIDS Prevention[J];Journal of Guangxi University For Nationlities(Philosophy and Social Science Edition);2005-02
5 YE Jing-rong,LI Yang,BAI Li-shi(Beijing Center for Disease Prevention and Control,Beijing 100013,China);Subtype and Sequence Analysis of gag Genes among HIV-1 Strains Circulating in Beijing during 2007[J];Chinese Journal of Virology;2009-06
6 CUI Wei-guo ,XING Hui ,WANG Zhe,et al. (Henan province Center for Disease Contral and prevention,Zheng Zhou 450003,China );Study on subtype and sequence of env gene among HIV-1 strain in Henan province[J];Henan Journal of Preventive Medicine;2005-01
7 TANG Li, WANG Xia, LIU Man-qing, ZHU Ze-rong, YANG Bei-fang, PENG Jin-song, YAO Zhong-zhao. Wuhan Municipal CDC of Hubei Province, Wuhan 430022,China;Related serological surveillance and analysis in 145 men who have sex with men in Wuhan City[J];Disease Surveillance;2006-12
8 FULi-jun, FANG Yi-rong, GUO Tian-ying. Shaoxing Municipal CDC of Zhejiang Province, Shaoxing 312041, China;Investigation of the sexual behaviors among the MSM in Shaoxing City of Zhejiang Province[J];Disease Surveillance;2007-12
9 HE Qun 1, WANG Ye 1, LIN Peng 1, ZHANG Zhou-bin 2, ZHAO Xi-xi 1, XU Hui-fang 2. 1.HIV/AIDS Institute, Guangdong Center for Disease Control and Prevention, Guangzhou 510300, China; 2.HIV/AIDS Division, Guangzhou Center for Disease Control and Prevention, Guangzhou 510300, China;KAP study on AIDS among men who have sex with men in Guangzhou, Guangdong province[J];Chinese Journal of Disease Control and Prevention;2005-02
10 Zhu Hong, Guo Hui, Chen Jianxiong, Liu Yi,et al. Beijing International Tralvel Healthcare Center, Beijing Administration of Entry - exit Inspection and Quarantine, Beijing, 100013;CLINICAL EVALUATION ON SEVERAL ANTI - HIV DIAGNOSTIC REAGENTS[J];Science of Travel Medicine;2001-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LU Bin2,XING Hui1,ZHAO Quanbi1,GENG Yunqi2,SHAO Yiming1(1National Center for AIDS/STD Prevention and Control,China CDC,Beijing 100050,China;2College of Life Sciences,Nankai University,Tianjin 300071,China);High Expression,Purification and Functional Analysis of the Tat Protein of HIV-1 B'/C Recombinant Strains in China[J];Chinese Journal of Virology;2002-04
2 Shao Yiming1 Zhao Quanbi1 Wang Bin1 Chen Zheng1 Su Ling1 Zeng Yi1 Zhao Shangde2 zhang Jiapeng2 Duan Yijuan3 Wolfgang Hell4 Hans Wolf4 1.Institute of Virology, CAPM, Beijing,100052 2.Yunngan Sanitation and Anti-epidemic Station 3.Ruili Sanitation and Anti;SEQUENCE ANALYSIS OF HIV env GENES AMONG HIV INFECTED DRUG INJECTING USERS IN DEHONG EPIDEMIC AREA OF YUNNAN PROVINCE,CHINA[J];CHINESE JOURNAL OF VIROLOGY;1994-04
3 LI Yan, XU Hui-fang, HAN Zhi-gang, et al. Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China;Sequence analysis of the C2-V3 region among HIV-1 strains found during 2004-2005 in Guangzhou[J];South China Journal of Preventive Medicine;2008-01
4 Yao Jun , Zhang Fujie, He Zhangping, et al. Beijing Ditan Hospital, Beijing 100011, P. R . China;Subtype and sequence analysis of the C2-V3 region of env gene among HIV-1 infected homosexual men in Beging[J];Journal for China AIDS/STD;2002-03
5 LI Yan,LIANG Caiyun,GAO Kai,et al.Guangzhou Center for Disease Control and Prevention(Guangzhou 510080,China);Assay of western blot bands pattern of antibody of 265 samples HIV-1 antibody positive[J];China Public Health;2005-11
6 WANG Zhe,XUE Xiao-ling,ZHAO Fei,et al.Henan Center for Disease Control and Prevention,Zhengzhou 450016,China;Analysis of Gene Sequence and Subtype of HIV Strains among 420 Positives in Southeast Area of Henan Province[J];China Preventive Medicine;2006-06
7 XING Hui *, LIANG Hao, HONG Kun xue, WEI Min, ZHAO Quan bi, FENG Yi, CHEN Jian ping, QUAN Yu, TENG Tao, SHAO Yi ming. *National Center for AIDS/STD Prevention and Control, Chinese Center for Disease Prevention and Control. Beijing 100050, China;The potential relationship between variation in the env V3-V4 region of HIV-1 predominant strains in China and virus biological feature[J];Chinese Journal of Microbiology and Immunology;2005-03
8 LU Lin, JIA Man-hong, ZHANG Xiao-bo, LUO Hong-bing, MA Yan-ling, FU Li-ru, LU Ji-yun.The Department of AIDS/STD, Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China;Analysis for epidemic trend of acquired immunodeficiency syndrome in Yunnan Province of China[J];Chinese Journal of Preventive Medicine;2004-05
9 WAN Zhuo-yue~* XING Hui LI Jie WANG Yu DIAO Li-mei MA Peng-fei LIN Peng JIANG Shu-lin SHAO Yi-ming. *Guangdong Provincial Center for Disease Control and Prevention,Guangzhou 510300,China;Subtype and sequence analysis of human immunodeficiency virus type-1 strains in Guangdong province[J];Chinese Journal of Preventive Medicine;2006-05
10 GUAN Qi*, WEI Min, HUANG Hai-long, XING Hui, HONG Kun-xue, MA Peng-fei, LIANG Hao, SI Xue-feng, HEI Fa-xin, ZHANG Zhuo-ran, SHAO Yi-ming.*National Center for AIDS/STD Prevention and Control, China Center for Disease Prevention and Control, Beijing 100050, China;Sequence analysis of gag-pol gene of HIV-1 B/C recombinant viruses in China[J];National Medical Journal of China;2004-05
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Shao Yiming;Guan Yongjiun Zhao Quanbi;Zeng Yi;Zhang Jiapeng; Zhang Yong; Duan Yijuan; Yang Guilin;Josef Kostler;Hans Wolf In 1995,26 IDUs and some of their spouses in Ruili, Yunnan Provinee were sampled.HIV-1 env genes were amplified by PCR from the cell;GENETIC VARIATIONS AND MOLECULAR EPIDEMIOLOGY OFTHE RUILI HIV-1 STRAINS OF YUNNAN IN 1995[J];Chinese Journal of Virology;1996-01
2 Bai Xuhua 1 Guan Yongjun 2 Zhang Yuanzhi 1 Shao Yiming 2 Wang Dongli 1 Su Ling 2 Liu Xiaoliang 2 Zhao Quanbi 2 Du Dawei 3 Josef Kostler 4 Hans Wolf 4;SUBTYPE AND SEQUENCE ANALYSIS OF THE C2-V3 REGION OF GENES OF MEMBRANE PROTEIN AMONG HIV-1 STRAINS IN WULUMUQI EPIDEMIC AREA OF XINJIANG[J];CHINESE JOURNAL OF VIROLOGY;1997-04
3 Qin Guangming *,Shao Yiming,Liu Gang,et al. *Sichuan Sanitation and Anti epidemic Station,Chengdu 610031;Subtype and Sequence Analysis of the C2-V3 Region of gp120 Genes among HIV-1 Strains in Sichuan Province[J];Chinese Journal of Epidemiology;1998-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved