Genetic Dissection and Molecular Dissection of Quantitative Traits
WU Wei Ren TANG Ding Zhong LI Wei Ming[WT6BX](Fujian Agricultural University: College of Crop Sciences, Fuzhou, 350002)[KH+3mmD][WT5HZ]
Most of the important characters in living beings are quantitative traits, which have complicated genetic basis and are very difficult for genetic research. Due to the rapid progress of molecular biological technology in the last two decades, especially due to the advent of molecular marker techniques and the techniques for the analysis and cloning of large DNA fragments, genetics has begun to march towards the great goal of elucidating the whole genomes of human and some model animals and plants, and the genetic and molecular dissection of quantitative traits (mapping and cloning of individual quantitative trait loci or QTL) has therefore become possible, and great progress has been achieved since late 1980′s. Studies in this field will enable us to perform precise analysis of QTL′s effects and reliable marker assisted selection of QTL and to realize genetic engineering of quantitative traits so as to make modern molecular biotechnology play even greater role in the genetic improvement of animals and plants and in the therapy of human′s genetic diseases. In this paper, recent progress in methodologies for the genetic and molecular dissection of quantitative traits is reviewed.
【CateGory Index】： Q348