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《Acupuncture Research》 1993-01
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INFLUENCES OF ACUPUNCTURE ON GASTRODUODENAL MUCOSAL LESION AND ELECTRICAL CHANGING INDUCED BY STRESS IN RATS

Xiang Limin Zhu Fengxian Ma Ying (Shuguang Hospital of Shanghai Traditional Chinese Medicine Cellege,Shanghai 300021) Weng Enqi Tang Guoying (Department of Environmental Science,East China Normal University,Shanghai 300062)  
Experiments were performed in 57 SD rats.The stress was induced by bi-nding plus revolving (5.5xg,170c/min,10min) or cold (0~4℃,30~60min).Selected acupuncture points were “Zusanli” and “Weishu”.Bipolar Ag-AgClrecording electrodes were respectively implanted on the serous membrane surfaceof the antrum,duodenum and on the abdominal skin corresponding to aboveareas.The results were as follows:(1) There are 63.2% individuals in thestress group which showed a large quantity of bleeding points spreading over thegastroduodenal mucosal membrane.The area density of lesion was 15.8~27.7%.Under microscope the signs emerged including mucosal blood vessel dilatationand hyperaemia,gland cell swelling,vi(?)lus broken and peeling off and lymph cellaccumulating,etc.84% individuals showed obvious inhibition of gastroduodenalelectroactivities including that the amplitude of slow wave was lower,the frequ-ency decreased even the rhythm was disordered,the number of fast wave redu-ced and the IDMEC (?) cycle was prolonged.(2)In the group of acupunctureplus stress only 16.7% individuals showed bleeding or hyperaemia,and the lesionarea density was only 1.7%.Also the pathohistological changes were obviouslydecreased.Gastroduodenal electrical changes were hardly seen (27.2%) or theinhibitory state above were significanly reduced (54.5%) when compared withthe stress group.There is strong reason to consider that acupuncture couldeffectively reduce the mucosal lesion and the electrical inhibition of stomachand duodenum induced by stress in rats.
【Fund】: 国家自然科学基金
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