Effects of Acupuncture Treatment on Blood LPO and SOD Contents in Parkinsonism Patients
Dong Xiaotong, Wang Shuangkun, Ren Xiaoqun, et al (Institute of Acupuncture and Moxibustion, China Academy of TCM, Beijing, 100700)
Objective: To observe effects of acupuncture treatment on blood LPO and SOD contents in Parkinsonism patients. Methods: 87 Parkinsonism patients were randomly divided into acupuncture group (n= 59) and medication group (n= 28). Acupoints as Xiaochan point (1.5 cun inferior to Shaohai HT 3), Waiguan (TE 5), Hegu (LI 4), Yanglingquan (GB 34), Taichong (LR 3), Zusanli (ST 36), etc were used and stimulated with uniform reinforcing reducing needling method. The treatment was given once daily, with 10 sessions being a therapeutic course, continuously for 3 courses. Patients in medication group were treated with madopar, sinemet, artane, etc based on the doctor's requirements. Plasma LPO content and SOD content of red blood cells were detected by using thiobarbituric acid via lipid peroxide malonyldialdehyde technique and radioimmunoassay respectively.Results: Results showed that after acupuncture treatment, SOD content increased significantly, particularly in patients above 60 years at age, female patients and the patients with disease duration being less than 3 years in comparison with those under 60 years , male patients and those with disease duration being over 3 years respectively. Conclusion: Acupuncture can function well in preventing Parkinsonism from exacerbation particularly in patients above 60 years old, female patients and those with shorter duration of disease.