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《Chinese Community Doctors》 2017-36
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Influence of "Tiao Zong Qi" prescription on calcium ion concentration in the genioglossus of aged rats with chronic intermittent hypoxia

Zhang Lixiu;Yang Haimiao;Zhu Tonggang;Liu Jimin;Chen Jia;Liu Tong;Affiliated Hospital of Changchun University of Traditional Chinese Medicine;  
Objective:To explore the influence of "Tiao Zong Qi" prescription on calcium ion concentration in the genioglossus of aged rats with chronic intermittent hypoxia.Methods:Animal models of chronic intermittent hypoxia were reproduced by hypoxia chamber,through the traditional Chinese medicine,sports,oxygen and other factors alone or combined application,we used colorimetric assay to quantify calcium concentration in the genioglossus of model animals.Results:In Chinese medicine group,the calcium ion concentration in the genioglossus was significantly increased compared with the aged rats model group(P0.05),in the chinese medicine + exercise group,the calcium ion concentration in the genioglossus was extremely significant increased compared with the aged rats model group(P0.01),in the chinese medicine+exercise+oxygen inhalation group,the calcium ion concentration in the genioglossus was extremely significant increased compared with the aged rats model group(P0.001).Conclusion:Traditional Chinese medicine,exercise and oxygen inhalation can improve the calcium ion concentration in the genioglossus of aged rats with chronic intermittent hypoxia,and the effect of combined application was the most obvious.
【Fund】: 吉林省教育厅项目(编号:吉教科合字[2016]第10号)~~
【CateGory Index】: R285.5
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