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《Modern Journal of Integrated Traditional Chinese and Western Medicine》 2011-15
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Protective effect of modified Huangqi Jianzhong decoction on gastric mucosa in rats with gastric ulcers induced by acetic acid

Fan Tuoying1,Zhou Hu2,Fan Qun3(1.The 94th Hospital of PLA,Nanchang 330002,Jiangxi,China;2.Donghu Hospital of Shenzhen,Shenzhen 518020,Guangdong,China)  
Objective It is to approach the protective mechanisms of modified Huangqi Jianzhong decoction on gastric mucosa in rats with gastric ulcers.Methods 60 Wistar rats were randomly divided into normal control group,model group,high does decoction group(20 g/kg),middle dose decoction group(10 g/kg),low dose decoction group(5 g/kg) and colloidal bismuth pectin group.There were 10 cases in each group.The model of chronic gastric ulcer was induced with 100% acetic acid.after treated with corresponding herbs for 16 days,the pathological of gastric mucosa,the blood prostaglandin(6-K-PGF1α),gastric juice epidermal growth factor(EGF),the stomach of nitric oxide(NO),blood super oxide dismutase(SOD) were observed.Results Modified Huangqi Jianzhong decoction promoted the rehabilitation of mucosa with gastric ulcer,and raised the levels of plasma prostaglandins,EGF in gastric juice,NO in gastric tissue and SOD in plasma.Conclusion Modified Huangqi Jianzhong decoction shows a protective effect on gastric mucosa in rats with gastric acid.
【CateGory Index】: R285.5
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Chinese Journal Full-text Database 4 Hits
1 YANG Xuesong; LI Yinong; YE Simao; DONG Xiuyun(Department of Gastroenterology, The Third Hospital,Beijing Medical University 100083);EXPERIMENTAL STUDY OF CORRELATION OF GASTRIC ULCER HEALING QUALITY WITH RISISTANCE TO REINJURY BY PREDNISONE IN RATS[J];Journal of Beijing Medical University;1996-06
2 ZHU Guo-qin, SHI Rui-hua. Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing (210029), China;The research progress of gastric mucosal protective drugs[J];International Journal of Digestive Disease;2006-05
3 ;Progress of Study on the Relationship of EGFR and its Signal Transduction Ways and Recovery of Gaster Mucosa Wound[J];Guiding Journal of TCM;2006-03
4 Liu Jinsong, Hou Xiaohua△ Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022;Protective Effect of Nitric Oxide on Gastric Mucosa[J];Acta Universitatis Medictnae Tangji;2004-05
Chinese Journal Full-text Database 10 Hits
1 LIU Jian-ping HU Dong-ju(Hospital of Traditional Chinese Medicine in Hebei Province,Shijiazhuang 050011);Study of Effect of Weixikang Apozema on Growth Factor of Acetic Acid Gastric Ulcer Rats[J];China Journal of Traditional Chinese Medicine and Pharmacy;2007-08
2 HONG Xiao-ping,MA Shu-mei.The sixth affiliated hospital of Sun Yat-Sen University,Guangzhou 510700,China;Clinical evaluation of montmorillonite powder in the treatment of the oral cavity ulcer[J];International Medicine & Health Guidance News;2009-18
3 WEI Wei,LIN Shou-ning,HUANG Gui-hua,TENG Jiu-xiang(TCM University of Hunan,Changsha,Hunan 410007,China);Effects of Anwei decoction on EGF of gastric ulcer in rats[J];Journal of Traditional Chinese Medicine University of Hunan;2008-06
4 Zhao Guangyi,Gao Linlin,Meng Lingxin.Department of Anesthesia,Second Affiliated Hospital,China Medical University,Shenyang 110004 CHINA;Effects of transection of the cervical sympathetic trunk on gastric mucosal blood flow and the changes of NO in water immersion restrain rats[J];The Journal of Clinical Anaesthesiology;2005-11
5 HUANG Gui-hua1,LIN Shou-ning1,WEI Wei2(1.Guangxi University of TCM,Nanning 530001,Guangxi,China;2.Digestion Department,Ruikang Affiliated Hospital of Guangxi University of TCM,Nanning 530001,Guangxi,China);Effects of Anweitang Granule on the EGF and EGFR Expression in Gastric Mucosa of Experimental Rats[J];Liaoning Journal of Traditional Chinese Medicine;2005-10
6 WANG Xiao-na1,ZHU Fang-shi2 (1.Nanjing University of Traditional Chinese Medicine,Najing 210028,Jiangsu,China;2.Academy of Traditional Chinese Medicine of Jiangsu Province,Nanjing,210028,Jiangsu,China);The Progress and Evaluation on Studies of Correlation Between Spleen Deficiency and Gastric Mucosa Defense Mechanism[J];Liaoning Journal of Traditional Chinese Medicine;2010-06
7 ZHANG Zhi-yong1,SUN Gong-kai2,YANG Shi-zhong2 (Affiliated Hospital of Hainan Medical University,Haikou 570102,China);Influence of appetite promotion decoction on the mucosal healing and EGF expression in gastric ulcer model mice[J];Journal of Hainan Medical University;2010-06
8 Yang Haifang1, Shi Zhaohong2, Zhang Jiemei2, Zhou Huifang1 (1.Hubei College of TCM, Hubei Wuhan 430061; 2.Wuhan Hospital of integration of traditional and werstern medicine.);Experimental Study of Cuyu Granule on Rats' Gastric Mucosa for Protective Effect[J];Journal of Shanxi College of Traditional Chinese Medicine;2006-01
9 WANG Lu sha 1 LIU You xiang 2 TU Qian 3 1Hubei Provincial TCM Hospital,Hubei 430061, China 2 Hubei College of TCM, 3Jianghan University;EFFECT OF ACUPUNCTURE OF "ZUSANLI" AND "WEISHU" ACUPOINTS ON EXPERIMENTAL GASTRIC ULCER[J];世界针灸杂志(英文版);2003-01
10 ZHANG Yong-feng1, LIU Ying-fang2, ZHANG Zhao-jie2, TAN Yong-gang2, YANG Min1, DING Min3 (1. Shenzhen Clinical Institute of Integrated TCM and Western Medicine, Guangdong Shenzhen 518035; 2. Shenzhen Second People's Hospital, Guangdong Shenzhen 518035; 3. Hubei College of Traditional Chinese Medicine, Hubei Wuhan 430061);The Effects of Jiechang Kangtai Recipe on Expression of EGFR and PCNA of Colonic Mucosa in Colitis Rats[J];Shenzhen Journal of Integrated Traditional Chinese and Western Medicine;2007-03
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 LI Jian-ling,YI Hong, FENG Xue-ping, et al.Medical Research Center, Xiangya Hospital, Central South University, Changsha ,410008, China;EGFR Activates AP-1 Through ERK-1/2 Signaling Pathway in the Rat Gastric Mucosal Cells[J];Journal of Chinese Physician;2003-09
2 Yu yanni,Fang Yi, Che Zhuping.Dept. of Pathology of Guiyang Medical Callege,Guigang 550004 [WT5”HZ];Expression of epidermal growth factor receptor(EGFR)in the biopsy materials of gastric ulcer[J];Guizhon Medical Journal;2000-06
3 ZHANG Wei-Ning; ZHANG Ye,LI Jia-Bang (1. Department of Internal Medicine, Futian District Hospital of Traditional Chinese Medicine,Shenzhen,Guangdong Province 518034, China; 2. Department of Obstetrics & Gynecology, First Affiliated Hospital, Hunan College of Traditional Chinese Medicine, Changsha, Hunan Province 410007, China; 3. Institute of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China);Effect of Jianwei Yuyang Granules on expression of epidermal growth factor receptor in gastric mucosa of gastric ulcer patients[J];Journal of Chinese Integrative Medicine;2004-01
4 HOU Xiao-Hua (Dept of Gastrorterology,Union Hospital, Tongji Medical University,Wuhan 430022);The effect of colloidal bismuth subcitrate on the gastric blood flow in rats with ethanol-induced gastric ulceration[J];Chinese Pharmacological Bulletin;1993-05
5 LIU Jian Ping,BO Tao,BAI Jian Le,HOU Xian Ming,LI Zhi Geng, HAN Yan,ZONG Quan He,CHEN Zhi Qiang, NIU Bing Zhan (Hebei Medical University, Shijiazhuang 050011 );The expression and significance of EGF,TGF-α and EGFR in the natural concrescence course of rats gastric ulcer[J];Chinese Pharmacological Bulletin;2003-10
6 ZHANG Shutian *, ZHANG Songhua, YU Zhonglin, WANG Yongfang. *Digestive Diseases Dep, Beijing Friendship Hospital affiliated to Capital University of Medical Sciences, Beijing 100050, China;The difference of the bismuth absorption from a single colloidal bismuth pectin therapy and quadruple therapy for eradicating Helicobacter pylori infection[J];National Medical Journal of China;2002-13
7 DENG Lan-qiong (Digestion Department of Internal Medicine, Hubei Hospital of TCM, Wuhan 430061, China);Effects of Chaihu Guizhi decoction on epidermal growth factor receptor of gastric ulcer mucosa of rats caused by acetic acid[J];Chinese Journal of Integrated Traditional and Western Medicine On Gastro-spleen;2005-03
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