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《Modern Journal of Integrated Traditional Chinese and Western Medicine》 2012-14
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Clinical study on the treatment with Chinese medicine sea buckthorn on non-alcoholic fatty liver

Li Yingchun1,Gao Zeli2,Zhang Cheng2,Fang Qi2,Yao Wei2,Jin LiWen2(1.Shanghai Baoshan Central Hospital,Shanghai 201900,China;2.ZhouPu Hospital of Pudong New District,Shanghai 201318,China)  
Objective It is to observe the clinical curative effect and safety of sea buckthorn on non-alcoholic fatty liver.Methods 86 patients with non-alcoholic fatty liver were randomly divided into treatment group with 44 cases,and control group with 42 cases,both the groups were given basic treatment such as control diet and physical exercise.Treatment group was given sea buckthorn capsule 1.5 g once time and three times per day at the same time,the treatment lasted for 90 days.Control group was given starch capsule with the same administration of treatment group at the same time.Before treatment and in 3 months after treatment,blood lipids,liver function,liver and spleen CT ratio and other indicators in both groups were observed.Results The improvements of the following indicators in treatment group compared with that in control group were significantly different(P0.05): total cholesterol,triglyceride,high density lipoprotein cholesterol,low-density lipoprotein cholesterol,alanine aminotransferase,hyaluronic acid,liver and spleen CT ratio,and blood glucose,blood urea nitrogen,serum creatinine were not statistically different.Conclusion Chinese medicine sea buckthorn capsules can improve blood lipids,ALT,and liver and spleen CT ratio level in patients with non-alcoholic fatty liver,while it will not lead to disorder of renal function and blood glucose metabolism.
【Fund】: 肝肾疾病病证教育部重点实验室(上海中医药大学)开放课题资助项目(09-SCYY008)
【CateGory Index】: R575.5
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