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《Modern Journal of Integrated Traditional Chinese and Western Medicine》 2014-24
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Study on the expression and correlation of RhoC and MMP-9 in pterygium specimens

Gu Qiuyan;Xingtai Medical College;  
Objective It is to observe the expression and correlation of RhoC protein and matrix metalloproteinases 9( MMP 9) in pterygium,and explore the feasibility by using RhoC and MMP-9 as a marker to evaluate pterygium biological characteristics. Methods The expression of RhoC and MMP-9 in 45 cases of primary pterygium and 16 cases of normal conjunctival tissue were detected by horseradish peroxidase labeled chain mildew avidin method of immunohistochemistry( S-P method). Results RhoC protein and MMP-9 protein expression in the tissue of pterygium were higher than that in normal conjunctival group,there was significant difference( P 0. 05). The correlation coefficient between RhoC and MMP-9 protein r = 0. 562,there is significant difference( P 0. 05). Conclusion The expression of RhoC and MMP-9 in pterygium can effectively determine the incidence and recurrence of pterygium,so as to take relevant measures in the early treatment,to alleviate the suffering and economic burden of patients.
【Fund】: 邢台市科学技术研究与发展计划项目(2013ZC176)
【CateGory Index】: R777.33
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