Studies of relation between bone quantity and bone quality in the elder with osteoporotic fracture
Liu Xingmo,Su Rukun,Ou PinzhongLiu Xingmo,Su Rukun,Department of Orthopedic Surgery,The 6th People' s Hospital of Guangzhou,Guangzhou 510655,Guangdong Province,ChinaOu Pinzhong,Department of Orthopedic Surgery,Second Affiliated Hospital of Guangzhou Medical College,Guangzhou 510655,Guangdong Province,China
AIM:To investigate interrelationship and regular rule between bone quality and bone quantity in the elder with femoral neck fractures.METHODS:Femoral heads from 37 aged patients, 18 men and 19 women, with femoral neck fracture were obtained after total hip replacement. The bone mineral density of all patients and all specimens of the femoral head were measured with DEXA.Cancellous bone samples were obtained from the femoral head. All samples were observed with scanning electron microscopy, and then the histomorphometric analysis was done. RESULTS:86.5%cases accorded with the diagnostic standard of osteoporosis(WHO).The proximal femural BMD in 43.2%cases were over the threshold value of fracture.As compared with the young adults,the old people presented obvious microstructural changes under electron microscopy. The result of histomorphometry showed: free end trabecular(FET) and mean trabecular plate separation (MTPS) were remarkably increased(P 0.01). Intertrabecular node(Tb.n), trabecular bone volume(TBV), mean trabeculaar plate thickness(MTPT) and mean trabecular plate density(MTPD) decreased(P 0.01)in the old people. CONCLUSION:Scanning electron microscopy and histomorphometry, adopted at femoral head from osteoporotic fracture,is a simple and accurate method for assessing the quantity and the quality of bone.
【CateGory Index】： R683