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《Chinese Journal of Clinical Rehabilitation》 2004-24
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Non-genetic features of peak bone mineral density in healthy women of Shanghai

Yue Juan Qin,Zhen Lin Zhang,Qi Ren Huang,Qi Zhou,Yun Qiu Hu,Miao Li,Yu Juan LiuYue Juan Qin,Zhen Lin Zhang,Qi Ren Huang,Qi Zhou,Yun Qiu Hu,Miao Li,Yu Juan Liu,Department of Osteoporosis,Prevention and Treatment Center for Osteoporosis,Sixth People's Hospital of Shanghai Jiaotong University,Shanghai 200233,China  
AIM:To investigate the relationship between peak bone mineral density(BMD) and non genetic factors in healthy Shanghai women,and to provide instructive evidence for preventing and treating osteoporosis.METHODS:BMD at lumbar spine(L1~4),proximal femur,greater trochanter and Ward's triangle were measured by duel energy X ray absorptiometry in 433 healthy women aged 20-40 years of Han nationality in Shanghai,and relative factors were investigated.RESULTS:The peak BMD was seen in 30-34 years at lumbar spine and 20-24 years at proximal femur respectively.BMD at all measurement sites were positively associated to body mass significantly(β=0.283-0.373,P 0.05),and negatively associated to menarche age(β=-0.151 to 0.093,P 0.001).Age was negatively related to BMD at greater trochanter and Ward's triangle(β=-0.137,-0.194,P 0.05) and height was positively associated to BMD at L1-4(β=0.152,P 0.05).Profession was also positively related to BMD at neck and Ward's triangle(β=0.001,0.116,P 0.05). No significant difference in age,height and body mass between women who began to drink milk from 0-18 years(group A) old and after 18 years old(group B,P 0.05).BMD in all site of group A were all higher than that of group B(P 0.05).CONCLUSION:Appropriate body mass,height,physical activity and milk consumption during childhood and adolescence are benefit in attaining higher peak BMD,and menarche delay is a risk factor for peak BMD.
【CateGory Index】: R58
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