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《Chinese Journal of Clinical Rehabilitation》 2004-32
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Related factors of occurrence and metastasis of colon carcinoma and RAB5A gene

Chun Mei Wang1,Xiao Bo Bu1,Jie Song1,Yan Long Han1,Ying Wang1, Kai Dong1,Jing Li2,Yu Mei Wang2,Jian Bo Yu2,De Wu Dong2, 1Department of Biology,2Department of Pathology,Mudanjiang Medical College, Mudanjiang 157011,Heilongjiang Province, hina  
AIM:To investigate the relationship between the expression of RAB5A gene and the occurrence and metastasis of colon carcinoma. METHODS:The expressions of RAB5A in 42 cases of colon carcinoma model were detected with immunohistochemical method. RESULTS:The expression of RAB5A was obviously correlated with the typing, differentiation of histology and metastasis of lymph node(χ2=3.96 to 6.73,P 0.05). CONCLUSION:RAB5A is a gene which is related with the occurrence and metastasis of colon carcinoma,and is related with their differentiation degree.
【Fund】: 黑龙江省高等学校骨干教师创新能力自助计划资助项目(1052G056)
【CateGory Index】: R735.35
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