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《Chinese Journal of Clinical Rehabilitation》 2005-10
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Correlation of development,metastasis and prognosis of breast carcinoma with expression of RAB5A gene

Bu Xiao bo1,Wang Chun mei1,Song Jie1,Han Yan long1,Wang Ying1,Li Jing2,Wang Yu mei2,Yu Jian bo2,Dong De wu2,1Department of Biology,2Department of Pathology,Mudanjian Medical College,Mudanjian 157011,Heilongjiang Province,China  
AIM:To investigate the role of high expression of RAB5A gene in the occurrence,development and metastasis of breast cancer.METHODS:Immunhistochemical technique was used to detect the expression of RAB5A gene in 46 cases of postoperative breast cancer provided by Mudanjiang Cancer Hospital between January and December 2003.RESULTS:The expression of RAB5A was not detected in normal tissues,but it was found in different degree in breast carcinoma tissues(P 0.01).CONCLUSION:RAB5A gene is possibly correlated with the occurrence and metastasis of breast carcinoma,and also with the differentiation degree of breast carcinoma.
【Fund】: 黑龙江省教育厅资助(1052G056)~~
【CateGory Index】: R737.9
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