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《Journal of Clinical Rehabilitative Tissue Engineering Research》 2008-31
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Quality of life in renal transplant patients versus hemodialysis patients

Guo Hong-bo Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China  
BACKGROUND: Renal replacement is a therapy for patients with nephropathy at final stage. Hemodialysis and renal transplantation are two effective treatments for nephropathy at final stage. OBJECTIVE: Using Brief Form of World Health Organization Quality of Life Questionnaire (WHOQOL-BREF) to compare and analyze the quality of life (QOL) and the factors influencing QOL in hemodialysis and renal transplant patients. DESIGN, TIME AND SETTING: The survey was performed at the Department of Urology, Beijing Friendship Hospital, Capital Medical University from January 2005 to January 2006. PARTICIPANTS: Sixty hemodialysis outpatients and 60 renal transplant patients from Beijing Friendship Hospital of Capital Medical University were enrolled. All patients were voluntary to participate in the questionnaire investigation. METHODS: There were two scales: ①General condition scale that evaluated the demographic data, clinical specifications, and complication conditions. ②WHOQOL-BREF involved four domains of physical capacity, psychological state, social function and environment, as well as the self-rating total scores by patients. A higher score indicated a better QOL. MAIN OUTCOME MEASURES: All patients were scored by each scale, and compared with the norms. The correlation between general condition of patients and the scores for each domain of QOL was analyzed. RESULTS: A total of 120 patients were all included in the final analysis. The overall score of QOL in hemodialysis patients was significantly lower than that in renal transplant patients (P=0.001). The score of physical capacity in hemodialysis patients was significantly lower than that of the norm (P 0.01). In hemodialysis patients, the score of psychological state was correlated with education (P 0.05); the score of social function was correlated with marital status and family income (P 0.05); the score of environment was correlated with education, family income, medical payment and the influence of medical fare (P 0.05-0.01); the overall score of QOL was correlated with family income (P 0.05). In renal transplant patients, the score of environment was correlated with family income and medical payment (P 0.05); the overall score of QOL was correlated with the duration after transplantation (P 0.05). CONCLUSION: The self-feeling of QOL in hemodialysis patients is worse than that in renal transplant patients. The QOL of hemodialysis patients is easily influenced by various factors compared with renal transplant patients.
【CateGory Index】: R699.2
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