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《Journal of Clinical Rehabilitative Tissue Engineering Research》 2009-18
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The role of Sertoli cells in the testes spermatogenesis and its damage in the radiation

Wang Yan-meiDepartment of Histology and Embryology,Medical College of Yan'an University,Yan'an 716000,Shaanxi Province,China  
A Sertoli cell resides in testicular seminiferous tubule,which is the only body cell contact with the spermatogenic cell,plays a crucial role of regulation in the process of spermatogenesis.Sertoli cells can provide a material basis and a favorable microenvironment for sperm.After X radiation,spermatogenic cells and mitochondrion dramatically swelling and lysis with a decrease of mitochondrial cristae,with the prolonging of time,the mitochondria damage get even worse,mitochondrial crista is disappeared.The results of the current study indicate that radiation can cause Sertoli cell damage,but the complete theoretical system remains unclear,which needs combines with other subjects for further study.
【Fund】: 陕西省教育厅自然科学基金项目(08JK504)~~
【CateGory Index】: R144
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