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《Journal of Clinical Rehabilitative Tissue Engineering Research》 2009-18
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The role of Sertoli cells in the testes spermatogenesis and its damage in the radiation

Wang Yan-meiDepartment of Histology and Embryology,Medical College of Yan'an University,Yan'an 716000,Shaanxi Province,China  
A Sertoli cell resides in testicular seminiferous tubule,which is the only body cell contact with the spermatogenic cell,plays a crucial role of regulation in the process of spermatogenesis.Sertoli cells can provide a material basis and a favorable microenvironment for sperm.After X radiation,spermatogenic cells and mitochondrion dramatically swelling and lysis with a decrease of mitochondrial cristae,with the prolonging of time,the mitochondria damage get even worse,mitochondrial crista is disappeared.The results of the current study indicate that radiation can cause Sertoli cell damage,but the complete theoretical system remains unclear,which needs combines with other subjects for further study.
【Fund】: 陕西省教育厅自然科学基金项目(08JK504)~~
【CateGory Index】: R144
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 PENG Ye1,CHENG Yicheng1,MEI Shenglin1,ZHANG Yuanqiang2,ZHANG Jinshan2,HO Wugang2(1.Department of Dentistry and Clinical Medicine,Fourth Military Medical University,Xi'an 710032,China;2.Department of Histology and Embryology,Fourth Military Medical University,Xi'an 710032,China);Early influnce on blood-testis barrier induced by electromagnetic pulse and expression of TGFβ3 in mouse testis[J];Chinese Journal of Stereology and Image Analysis;2007-01
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 HAN Da-li1,WANG Xiao-yun1,XING Xin1,ZHOU Guang-dong2,LIU Wei2,CAO Yi-lin21.Department of Plastic & Reconstructive Surgery,Shanghai Changhai Hospital,the Second Military Medical University,Shanghai 2004332.Department of Plastic & Reconstructive Surgery,9th People's Hospital,School of Medicine,Shanghai Jiaotong University Shanghai 200011;Basic biological characteristics of Sertoli cells[J];Journal of Reproductive Medicine;2008-05
2 Mai QP, Xie JS, Huang RY, Su WX, Yang JA Department of Histology and Embryology, Youjiang Medical College for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China;Research progress and future application of Sertoli cells[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-43
3 Wang Yan-mei Department of Histology and Embryology,Medical College of Yan’an University,Yan’an 716000,Shaanxi Province,China;X-ray ionization radiation-induced injury to adult mouse testis tissue[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2009-20
4 WANG Yan-mei,YANG Jia-zhou,AI Qing-yan,ZHAO Yu-feng,MIAO Nai-zhou(Medical College of Yanan University,Department of Histology and Embryology,Yanan,716000);Effect of X-ray irradiation on structure of spermatogenic epithelium in mouse testis[J];Journal of Yanan University (Medical Sciences);2008-03
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Chinese Journal Full-text Database 3 Hits
1 WANG Shui ming, WANG De wen, PENG Rui yun, GAO Ya bing, HU Wen hua, YANG Yi, CHEN Hao yu, CUI Xue mei, GU Qing yang Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850;Effect of electromagnetic pulse irradiation on ultrastructure of spermatogenic cells in mice[J];Journal of Reproductive Medicine;2003-04
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