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《Journal of Clinical Rehabilitative Tissue Engineering Research》 2009-18
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Pretreatment of interleukin-2 receptor monoclonal antibody combined with immunoadsorption in 24 sensitized renal allograft recipients

Xing Li,Cai Wen-li,Miao Shu-zhai,Qu Qing-shan,Wang Pei-yu,Wang Kai Department of Organ Transplantation,the People's Hospital of Zhengzhou,Zhengzhou 450003,Henan Province,China  
Recently years,with the rapid development of organ transplantation technique,especially the maturation of management in perioperative period of kidney transplantation,the number of sensitized renal allograft recipients whose panel reactive antibody were positive increased,and it is easy to occur acute rejection which can result in delaying the recovery of graft function,even transplant failure.Though pretreatment of interleukin-2 receptor monoclonal antibody(basiliximab) combined with immunoadsorption in sensitized renal allograft recipient,the article was designed to observe the occurrence of acute rejection and to compare with normal renal allograft recipient.Results showed that there is no significant difference in the occurrence rates of acute rejection between the sensitized and normal renal allograft recipients.Results suggest we could securely performed the renal homotransplantations after the panel reactive antibody levels decreased to normal by pretreatment of interleukin-2 receptor monoclonal antibody(basiliximab) combined with immunoadsorption in sensitized renal allograft recipients.
【CateGory Index】: R699.2
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