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《Chinese Journal of Tissue Engineering Research》 2012-09
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Total knee arthroplasty for the treatment of knee osteoarthritis caused by endemic skeletal fluorosis

Luo Rui1,Liu Ri-guang1,Ye Chuan1,Yu Yan-ni2,Guan Zhi-zhong2 1Department of Orthopedics,Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou Province,China;2Department of Pathology,Guiyang Medical Collage,Guiyang 550004,Guizhou Province,China  
BACKGROUND:Knee osteoarthritis caused by endemic skeletal fluorosis is a complex and chronic systemic disease,which can cause the damage of surrounding bone and sclerotin of knee joint.OBJECTIVE:To investigate the effect of total knee arthroplasty (TKA) in the treatment of knee osteoarthritis caused by endemic skeletal fluorosis.METHODS:Nine patients suffered from knee osteoarthritis caused by skeletal fluorosis that diagnosed by local epidemiology,dental fluorosis,clinical and imaging from March 2010 to October 2011 and all the patients were treated with bilateral TKA.The clinical efficacy was evaluated according to the knee scoring system of United States Hospital for Special Surgery before arthroplasty and final follow-up after arthroplasty.RESULTS AND CONCLUSION:Score results showed that 5 knees were excellent,3 knees were good and 1 knee was fair after knee arthroplasty.All patients have been improved in pain,function and range of motion.TKA is an effective method for the treatment of knee osteoarthritis caused by skeletal fluorosis.
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【Fund】: 2010年度国际合作计划专项经费项目(2010DFB30530) 课题名称:地方性氟中毒发病机制及防治研究~~
【CateGory Index】: R687.4
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