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《Chinese Journal of Tissue Engineering Research》 2014-20
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Influence of geniposide on collagen II synthesis of cultured chondrocytes in vitro

Tan Yu-lin;Bao Tong-zhu;Liu Qin;Han Yu;Wang Yan-lin;Liu Yang;Zhou Na-xin;Yan Fei;Zhao Long-tao;The First College of Clinical Medical Science, Three Gorges University;Yichang Central People's Hospital;Institute of Molecular Biology, Medical College, Three Gorges University;  
BACKGROUND: Chinese herb Cape Jasmine Fruit can activate the chondrocytes and geniposide is an important component in this herb. OBJECTIVE: To investigate the effect of geniposide on collagen II synthesis in rat chondrocytes cultured in vitro. METHODS: Rat chondrocytes were separated and cultured in vitro. The chondrocytes were then interfered with 25, 50 and 100 mmol/L geniposide. Normal control group was also set. Collagen II mRNA and protein expression was detected with semi-quantitative RT-PCR and western blot analysis, respectively. RESULTS AND CONCLUSION: RT-PCR and western blot analysis results showed that, geniposide at 25, 50 and 100 mmol/L increased the collagen II mRNA and protein expression(P 0.01). Geniposide can promote the synthesis of collagen II in rat chondrocytes cultured in vitro.
【Fund】: 湖北省自然科学基金(2010CDB10701)~~
【CateGory Index】: R329.2
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【References】
Chinese Journal Full-text Database 1 Hits
1 Zhu Zhijian;Yu Yanni;Tao Xin;Department of Pathology,Guiyang Medical College;;Effects of ColⅡexpression in different concentrations of fluoride in rat primary chondrocytes[J];贵州医药;2015-07
【Citations】
Chinese Journal Full-text Database 3 Hits
1 DING Song-tao1,LIU Hong-tao2,LI Wen-min1,LI Xiu-ying1,YU Chao1(1.Institute of Life Science,Chongqing Medical University,Chongqing 400016,China;2.Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian Liaoning 116023,China);Protective effects of geniposide on human umbilical vein endothelial cell injury induced by H_2O_2 in vitro[J];中国药理学通报;2009-06
2 Ma Yan, Jin Jiahong, Zhao Weizhong et al(Dept of Pharmacology , Anhui Medical University,Hefei 230032);Protective effect of total glycosides of Zhizi on experimentalacute gastric mucosal lesion induced by aspirin[J];安徽医科大学学报;2004-05
3 Department of Pharmacology, Medical College of CPAPF (Tianjin 300162) Zhu Jiang and Cai Dehai Tianjin Institute for Drug Control Rui Jing;Antiinflammatory and Analgesic Effects of Cape Jasmine (Gardenia jasminoides)[J];中草药;2000-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Yu;CHENG Saibo;ZHOU Fenghua;ZHANG Lei;SU Zhijie;ZHAO Dandan;CHEN Yuyao;JIA Yuhua;School of Traditional Chinese Medicine of Southern Medical University;;Effects of Geniposide on Inflammation and Oxidative Stress of Apo E Knockout Mice with Atherosclerosis and None-alcoholic Fatty Liver Disease[J];中药新药与临床药理;2015-05
2 WANG Shi-cai;CHEN Tai-jun;HUANG Mei-song;ZHU Shao-ming;Department of Internal Medicine,Shiyan Hospital of Integrated Traditional and Western Medicine;;Protective effect of BNDF on vascular endothelial cells with H_2O_2-induced oxidative injury[J];中国病理生理杂志;2015-08
3 DONG Hongzhen;ZHANG Wei;The First Hospital Affiliated to Guangzhou University of Traditional Chinese Medicine;;The Clinical Curative Effect of Reduning Injection on Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease Syndrome of Phlegm Heat Obstructing in the Lung[J];中国中医急症;2015-08
4 YU Huiling;ZHANG Xiaoshuang;ZHANG Enhu;Shaanxi University of Chinese Medicine;;Re-evaluation on Literature Relevant to Analgesic Action of Heat-clearing Medicine[J];现代中医药;2015-04
5 XIN Ying;College of Mongolian Medicine and Pharmacy, Inner Mongolia University for the Nationalities;;Review of Anti-inflammatory Effect of Mongolian Medicine and Its Active Ingredients[J];中国现代应用药学;2015-06
6 ZHU Di-na;XIN Wen-feng;ZHANG Wen-sheng;Protection and Utilization of Chinese Medicine Resources of Beijing Key Laboratory,Beijing Normal University;;Research progress on the molecular mechanism of geniposide for diabetes and its complications treatment[J];环球中医药;2015-05
7 HU Zhefu;TANG Qizhu;LIU Yuan;LI Jin;ZHANG Wenbin;Department of Cardiology,Renmin Hospital of Wuhan University;;Effect of hesperetin on cardiac fibroblast proliferarion induced by TGF-β_1[J];疑难病杂志;2015-04
8 SHEN Yi;SUN Pei-na;FENG Xiao-hong;The Third Clinical Medicine College, Zhejiang Chinese Medical University;Zhejiang Provincial Hospital of TCM;;Theoretical and Research of Gardenia in Treating Hyperlipidaemia[J];江西中医药大学学报;2015-01
9 HOU Xiaoli;SUN Mingxue;GAO Huanhuan;XIAO Kai;Lab of Toxicology and Pharmacology,Faculty of Tropical Medicine and Public Health,Second Military Medical University;;Progress on anti-inflammatory natural products[J];药学实践杂志;2015-01
10 DUAN Li-ge;CAI Xiao-shuang;HE Jing-ren;LIU Zhi-wei;KUANG Min-jie;LIU Gang;School of Food Science and Engineering,Wuhan Polytechnic University,Hubei Provincial Key Laboratory for Agricultural Products Processing and Conversion;Inspection and Test Center of Wuhan Polytechnic University for Quality of Cereals,Oils & Foodstuffs;Hubei Zhongke Ziguang Technology Co.,Ltd.;;Purification and Preparation Techniques for Geniposide of Medium Purity[J];中国调味品;2014-11
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Jiang Ping;Wei Peng;Zhao Ming-cai;Chen Qiong;Wang Zi;Department of Orthopedics, Affiliated Hospital of North Sichuan Medical College;;Effect of type I or type Ⅱ collagen on biological characteristics of human chondrocytes[J];中国组织工程研究;2014-30
2 Tan Yu-lin;Bao Tong-zhu;Liu Qin;Han Yu;Wang Yan-lin;Liu Yang;Zhou Na-xin;Yan Fei;Zhao Long-tao;The First College of Clinical Medical Science, Three Gorges University;Yichang Central People's Hospital;Institute of Molecular Biology, Medical College, Three Gorges University;;Influence of geniposide on collagen II synthesis of cultured chondrocytes in vitro[J];中国组织工程研究;2014-20
3 Yan Hu;Su You-xin;Lin Xue-yi;Chen Bao-jun;Zhou Bi-hong;Zhang Qing;Fujian University of Traditional Chinese Medicine;;Culture of rabbit's articular chondrocytes using type Ⅱ collagenase enzyme digestion method[J];中国组织工程研究;2013-50
4 Ran Longyan1,Gui Chuanzhi2,Huang Xin1,Guan Zhizhong2* 1.Department of Pathology,Staff Hospital of Electric Power in Guizhou,,Guiyang 550002,China.2.Department of Pathology,Guiyang Medical College,Guiyang 550004,China.;Research of ERK/p-90RSK signal transduction pathway in the brains of rats with coal-buring fluorosis[J];贵州医药;2013-01
5 CUI Cai-yan1,LI Hua-bing2,LIU Ke-jian1,HE Xiao-hong3,LI Chang-cheng1,YANG Ji-xian3,LIU Xiao-li1,YU Bin3,ZHANG Yu-zeng1(1.Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China;2.Hubei Jianshi Center for Disease Control and Prevention,Jianshi,Hubei 445300,China;3.Hubei Enshi Center for Disease Control and Prevention,Enshi,Hubei 445000,China);A Probable Correlation between Serum SOST Expression and Fluoride Bone Injury among Fluoride Exposed Population[J];环境与职业医学;2012-02
6 Li Chong-bin,Sun Fa,Xiao Yue-hai,Shi Jia-qi,Gu Jiang,Liu Xian-lin,Chang Ao-shuang,Xie Chun.Department of Urology,the Affiliated Hospital of Guiyang Medical College,Guiyang,550004,Guizhou,China.Department of Electron Microscopy,Guiyang Medical College,Guiyang,550004,Guizhou,China.College of Public Health,Guiyang Medical College,Guiyang,550004,Guizhou,China.;Effects of coal-burning fluorosis on the ultrastructure of rat testis[J];贵州医药;2011-02
7 WANG Ning,FAN Yu-lan,DONG Miao-zhu,et al(Department of Toxicology,Shanghai Municipal Center for Disease Control and Prevention,Shanghai 200336,China);Effects of Excess Fluoride on Rat Chondrocytes in Vitro[J];职业卫生与应急救援;2010-05
8 LI Liang-zhong,ZHANG Hong-yin, LIU Kai-tai(Department of stomatology,Hospital of Peking University,Peking 100871);Effects of fluoride on ultrastructure of chondrocyte of culture in vitro[J];中国地方病防治杂志;2009-03
9 XU Peng ,GUO Xiong,YAO Jianfeng,ZHANG Fujun,GENG Dong,DU Xiaoyang,CAI Qiankun. Department of Bone and Joint Diseases,Xi′an Red Cross Hospital,Xi′an710054,China;Effect of excess fluoride on chondrocyte differentiation and phenotypic expression of type Ⅱ and Ⅹ collagens of cartilages from experimental rats[J];中华风湿病学杂志;2002-04
10 XING Dan~*,MA Xin-long,MA Jian-xiong,CHEN Yang,XU Wei-guo,WANG Jie,YA NG Yang,ZHU Shao-wen,MA Bao-yi,FENG Rui.*Department of Orthopaedics Institute, Tianjin Hospital,Tianjin 300211,China;The effects of different intensities of treadmill running on the expression of MMP-3,COL-Ⅱand TIMP-3 in the articular cartilage of rats[J];中华骨科杂志;2013-02
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 ZHANG Jian,WEI Xin-bing,DING Hua,LOU Hai-yan(Institute of Pharmacology,Medicine College of Shandong University,Jinan 250012,China);Protective effects of carvedilol on oxidative stress injury induced by hydrogen peroxide in vascular endothelial cells[J];中国药理学通报;2006-05
2 CHENG He Li,ZHAO Xin Min 1 (Dept of Pharmacy , the First Affiliated Hospital of Anhui Medical University,Hefei 230022; 1Liansheng Science and Trading Co.Ltd,Hefei 230022);The eperimental research of anti-inflammation effect of jasminoidin[J];安徽医药;2004-03
3 HONG Hao, LIU Guo Qing (Dept of Pharmacology, China Pharmaceutical University, Nanjing 210009);Strategies against oxidative stress for therapy of ischemic cerebrovascular diseases[J];中国药理学通报;2004-01
4 Shen Guo-ming,et al (Anhui College of Traditional Chinese Medicine,Hefei 230038);EXPERIMENTAL STUDY ON THE EFFECT OF ELECTROACUPUNCTURE ON VASOACTIVE INTENSTINAL PEPTIDE IN RAT WITH GASTRIC MUCOSAL DAMAGE[J];中国中医药科技;2002-06
5 XIE Xue jian, ZHANG Jun hui, MA Ai hua (Nanjing General Hospital of Nanjing Command, Nanjing, Jiangsu 210002, China);Evolved Investigation of Chinese Traditional Medicine-Gardenoside[J];时珍国医国药;2000-10
6 Department of Pharmacology, Medical College of CPAPF (Tianjin 300162) Zhu Jiang and Cai Dehai Tianjin Institute for Drug Control Rui Jing;Antiinflammatory and Analgesic Effects of Cape Jasmine (Gardenia jasminoides)[J];中草药;2000-03
7 Yao Quansheng, Zhou Guolin, Zhu Yanqin, Pan Yuying Hu Junhong, Xue Huizhong Zhang Qin (Nanjing Institute of Materia Medica 210009);Screening Studies on Anti-inflammatory Function of Traditional Chinese Herb Gardenia jasminoides Ellis and Its Possibility in Treating Soft Tissue Injuries in Animals[J];中国中药杂志;1991-08
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