Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《The Chinese Journal of Modern Applied Pharmacy》 2005-01
Add to Favorite Get Latest Update

Effect of polysaccharide from Allium sativum L. on coxsackievirus group B type 3 in vitro

ZHENG Min,MEI Xian-chen, BAO Cui-yu,WU Ji-liang, LI Li-zhong, CHENG Hong-guang(Department of Pharmacology , Xianning College ,Xianning, 437100,China)  
OBJECTIVE To invesigate the inhibitory effects of polysaccharide from Allium sativum L. on Coxsackievirus group B type 3(CVB_3)in vitro.METHOD The following experiments about polysaccharide from Allium sativum L. A , B and C were performed: the cytotoxicities test on Hep-2 cell, the direct inactivation of CVB_3,the inhibition of CVB_3 adsorption and biosynthesis.RESULTS The 50% toxic concentration (TC_ 50) of polysaccharide from Allium sativum L. A , B and C on Hep-2 cell were 1000,800 and 4000μg/mL respectively. The above three components showed no direct inactivation of CVB_3 or inhibition of CVB_3 virus adsorption. With the exception of polysaccharide from Allium sativum L. A, components B and C could dose-dependently inhibit CVB_3 biosynthesis. CONCLUSION polysaccharide from The Allium sativum L. B and C can produce obvious inhibitory effects on Coxsackievirus group B type 3(CVB_3) in vitro by prevention of CVB_3 biosynthesis.
【Fund】: 湖北省教育厅重点项目(2003A004)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 LIU Zheng-jun;Shanxi University of Chinese Medicine;;Overview of the biological activity of Plant Polysaccharides[J];海峡药学;2014-05
2 ZHOU Jinghua1,LI Hanwei2,WAN Shunkang1,ZHANG Cuixiang1(1.Pre-clinical College,Dali University,Dali,Yunnan 671000,China; 2.Dali Affiliated Hospital of Dali University,Dali,Yunnan 671000,China);Research Review into the Polysaccharide Structure and Biological Activity of Garlic[J];大理学院学报;2010-12
3 DENG Gui-chun,SUN Jing-yi,ZHANG Yi-xin(College of Chemistry,Liaoning University,Shenyang 110036,Liaoning,China);Study on Polysaccharide Distributing in Different Time Ginkgo Leaf[J];辽宁大学学报(自然科学版);2010-04
4 GAO Li1,WANG Qiang2,PATIGUL Mahmut1,(1.College of Life Science and Technology,Xinjiang University,Urumqi 830046,China ;2.Test Center of Physical and Chemical Characteristic,Xinjiang University,Urumqi 830046,China);Isolation,Purification and Monosaccharide Composition Analysis of Polysaccharide from Diaphragma of Juglans regia L.[J];食品科学;2010-21
5 CHEN Jin-ling,GUO Mo-ting,CHEN Xiao-lei,HUANG Xue-song* (Department of Food Science and Engineering, Jinan University,Guangzhou 510632,China);Preparation and identification of carboxymethyl garlic polysaccharide[J];食品工业科技;2010-07
6 ZHANG Xiao-fang,ZhAO Jian-xiong.Lanzhou University,The First People Hospital of Lanzhou,Lanzhou,730000;The Radiosensitizing Effects of Grape Seed Procyanidin Extract on Lung Cancer Cell Line SPC-A-1[J];实用癌症杂志;2010-03
7 ZENG Qing-hua et al (College of Chemistry and Chemical Engineering,Liaocheng University,Liaocheng,Shandong 202059);Determination of Carbohydrates in Allium sativum L. by High Performance Liquid Chromatography with Evaporative Light Scattering Detection[J];安徽农业科学;2008-32
8 LIANG Li-jun,ZENG Zhe-ling ,XIONG Tao,L Wei (State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047,China);Determination of Content of Polysaccharide in Garlic Seed by Anthrone-sulfuric Method[J];食品科学;2008-09
9 HUANG Ting-ting1,SHANG Xue-jun1,YAO Gen-hong2,GE Jing-ping3,TENG Wen-hui1,SUN Yi1,HUANG Yu-feng1 1.Department of Andrology,2.Department of Blood Transfusion,3.Department of Urology,Nanjing University School of Clinical Medicine /Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu 210002,China;Grape Seed Extract Inhibits the Growth of Prostate Cancer PC-3 Cells[J];中华男科学杂志;2008-04
10 GAO Ai-xia1, LUO Ju-dong2, WU Qing-ting3, LI Hou-da3, XUE Zhi-mou1(1. Animal Experiment Centre of School of Soochow University, Suzhou 215123, China,2. Dept. of Radiation Oncology Shanghai No 6 Hospital of Jiaotong University, Shanghai 200233, China3. College of Animal Science and Veterinary Medicine of Yanzhou University, Yanzhou 225009, China);Antitumor Effect of Anthocyanidin on Lung Cancer NCI-H460 Cells in vitro and in vivo[J];实验动物与比较医学;2008-02
China Proceedings of conference Full-text Database 1 Hits
1 KONG Xiang-zhi HUANG Xue-song (Department of Food Science and Engineering,Jinan University,Guangzhou,Guangdong,China,510632);Effect of modified pH before or after macroresin column on the garlic polysaccharide and alliinase[A];[C];2008
【Citations】
Chinese Journal Full-text Database 5 Hits
1 ZHENG Min ,PAN Shi-bin JIANG You-ding ,et al (Department of Pharmacology, Xianning College, Xianning Hubei 437100, China );An Acute Toxicity Testing of the Allium Sativum L Polysaccharide and It's Effect on the Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) in Injured Mice Serum or Liver[J];咸宁学院学报(医学版);2003-02
2 WANG Zhi jie 1,YANG Zhan qiu 1, HUANG Tie niu 2, WEN Li 1, LIU Yan wen 3 (1.Virus Research Institute, Hubei Medical University, Wuhan 430071,Hubei, China; 2. Midsouth University of Finance and Economics, Wuhan 430064,Hubei, China; 3.Depart;Experimental Research on Inhibitory Effect of Alcohol Extracts from Loranthus yadoriki Sieb. on Coxsackie B_3 Virus[J];中国中药杂志;2000-11
3 GONG Xiao Jian, JI Hui, LU Shun Gao, LI Shao Ping 1, LI Ping 1 Department of Pharmacology, 1Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210009;Effects of Polysaccharides from Cultured Cordyceps sinensis on Murine Immunologic Function[J];中国药科大学学报;2000-01
4 Shen Yuanying(申元英), Yang Zhanqiu(杨占秋), Liu Jianjun(刘建军), et al. (Hubei Medical University, Hubei 430071);Anti-Coxsackievirus B_3 Activity of Rheum Offinicale Extraction in Vitro[J];北京中医药大学学报;1999-05
5 WangZhijie (Virus research institute,Hubei medical university,Wuhan 430071);THE PRIMARY INVESTIGATION OF EFFECTS ON HSV2 AND CVB3 VIRUS OF EMODIN OF RHIZOMA POLYGONI CUSPIDATI[J];安徽中医学院学报;1999-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Yan;WEI Gang;ZHU Fenglin;GUO Yunke;PING Fang;JING Rongyue;LU Tulin;GUO Haiying;WANG Yue;Nanjing University of Chinese Medicine;;Xinbitongling on mice immune function[J];长春中医药大学学报;2015-05
2 Meng Xianjun;Zhu Anning;Xu Weiwei;Department of Traditional Chinese Medicine in Medical College,Xiamen University;;The Modern Research and Application of Pueraria Flower Liquor-Resolving Decoction[J];光明中医;2015-07
3 SHEN Wei;HU Ling-ling;LI He-yu;HU Gao-sheng;Shandong College of Traditional Chinese Medicine;The First Peoples' s Hospital of Jimo City;Tianjin Ubasichealth Nutrition Co.,Ltd.;School of Traditional Chinese Material Medica,Shenyang Pharmaceutical University;;Studies on Adenosine Accumulation in Two-Stage Cultured Cordyceps sinensis Mycelium[J];食品研究与开发;2015-14
4 BAO Hai-Ying;SUN QI;HUANG Wei;SUN Xue;BAU Tolgor;LI Yu;College of Chinese Medicinal Material, Jilin Agricultural University;Engineering Research Center of Chinese Ministry of Education for Edible and Medicinal Fungi, Jilin Agricultural University;;Immunological regulation of fermentation mycelia of Fomitopsis pinicola on mice[J];菌物学报;2015-02
5 HAN Xiao-juan;SHEN Shan-mei;TCM and Western Medicine Integration Department,Nanjing Gulou Hospital Affiliated to Nanjing Traditional Chinese Medicine University;Endocrinology,Yancheng TCM Hospital Affiliated to Nanjing Traditional Chinese Medicine University;Department of Endocrinology,Gulou Hospital Affiliated to Medical School of Nanjing Medical University;;Research Progress of Pharmacological Activities and Mechanisms of Cordyceps Polysaccharide[J];医学综述;2014-16
6 SUN Lian-hai;GUO Ming-yue;Department of Basic Medical Sciences,Luohe Medical College;Department of food engineering,Luohe Medical College;;Impact of Fermented Milk Beverage with Cordyceps Militaris on the Immune Function of Mice[J];中国食物与营养;2014-06
7 NIU Xiao-hui;HUA Dong;Chemical and Life Science College,Changchun University of Technology;;Research on the Extraction Technique of Alliumsativum L. Polysaccharides by RSM[J];中国调味品;2014-05
8 Gao Lingfei;Wang Yixiang;Weng Boqi;College of Resource and Environment, Fujian Agriculture and Forestry University;Agricultural Ecology Institute,Fujian Academy of Agricultural Sciences;;Progress of Study on the Industrial Cultivation and Series Processing Technology of Cordyceps militaris[J];中国农学通报;2014-13
9 YANG Huai‐Jun;GUO Su‐Ping;XUE Li;Shanxi Institute for Medicine and Life Science;;Auxiliary protective effects of the mycelial extracts from Ophiocordyceps sinensis on chemical‐induced liver injuries in mice[J];菌物学报;2014-02
10 ZHANG Xue;SUN Yu-jiao;QIAO Yuan;HE Yong-lan;SHI Chuan-lin;CHEN Li;WANG Yao-fei;HAN Li-qin;School of Pharmacy,Jilin Medical College;;Study the antioxidant of total flavonoids in fairy grass[J];吉林医药学院学报;2014-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Li-jiao1,FEI Rui2,GAO Li-hong1,WANG Shu-xiang2,TONG Ju-hui3 (1.School of Life Science,Changchun Teacher University,Changchun,Jilin 130032;2.School of Norman Bethune Medical Science,Jilin University,Changchun,Jilin 130021 3.Stomatology Hospital,Jilin University,Changchun,Jilin 130041);Research Progress on Anti-inflammatory Activities of Polysaccharides from Plant[J];北方园艺;2010-20
2 WANG Chang-zhen①,CONG Jian-bo①,XIAN Hong①,HU Xiang-jun①,LI Yan②,GUO Qi②,CHEN Peng①,SUN Cun-pu①,WU Ke①①Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China;②Institute for Drug and Instrument Control of Beijing Military Region,Beijing 100071,China;Purification of Sulfated Polysaccharide from Laminaria Japonica and Studies of its Anti-tumor Mechanism[J];解放军药学学报;2010-04
3 YUAN Congying~(1,2),CHE Wenwen~2,ZHANG Ning~2,WANG Sumin~(1*)(1.Pharmacology Department,Basic MedicalCollege,Hebei Medical University,Shijiazhuang 050017,China;2.ShijiaZhuang Vocational Technology Institute,Shijiazhuang050000,China);Research Progress and Develop Prospect of Natural Plant Polysaccharides[J];中国现代应用药学;2009-12
4 MAO Shu-mei,LI Cheng-de,WANG Lin,WANG Jin-hong,DAI Gong,KANG Bai(Dept of Pharmacology,Weifang Medical College,Weifang Shandong 261042,China);Effect and mechanism of astragalus polysaccharides on apoptosis of the islet beta cell in diabetes mellitus rats[J];中国药理学通报;2009-09
5 LU Wei1,2,ZENG Zhe-ling1,2,DAI Zhi-kai1,2,HAO Chun-qing1,2 (1. State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; 2. College of Life Science and Food Engineering, Nanchang University, Nanchang 330031, China);Extraction and Structural Analysis of Garlic Polysaccharide[J];食品科学;2009-18
6 HUANG Xue-song,LI Ying-si,SHI Si-mi(Department of Food Science and Engineering,Jinan University,Guangzhou,Guangdong,510632,China);Study of Functions and Properties of Garlic Polysaccharide[J];现代食品科技;2009-06
7 ZENG Zhe-ling,LIANG Li-jun,JI Chuang,XU Di(State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047,China);Study on the optimization of extraction technology and antioxidation activity of garlic polysaccharide[J];食品工业科技;2009-04
8 WANG Yan-mei,GAO Li,LIU Meng,Patigul Mahmut(College of Life Sciences and Technology,Xinjiang University,Urumqi 830046,China);Study on chemical constituents of the diaphragma of Juglans regia L.[J];食品工业科技;2008-12
9 Lü Shao-yi1,SHAO Zi-qiang1,2,WANG Fei-jun1,LIAO Bing2,LIU Yong-liang1,WANG Wen-jun1(1.School of Materials Science and Engineering,Beijing Institute of Technology,Beijing 100081,China;2.Key Laboratory of Cellulose and Lignocellulosics Chemistry,Guangzhou Institute of Chemistry,Chinese Academy of Sciences,Guangzhou 510650,China);Influence of different alkali metal hydroxide on carboxymethylation of cellulose[J];应用化工;2008-08
10 YANG Jing,WANG Yang,KONG Xiang-zhi,YAN Jin-kui,HUANG Xue-song(Department of Food Science and Engineering,Jinan University,Guangzhou 510632,Guangdong,China);PREPARATION OF GARLIC POLYSACCHARIDE OCTENYLSUCCINATE[J];食品研究与开发;2008-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 WANG Yidan;WANG Liang;LIU Bingyan;Biological Engineering Branch,Jilin College of Engineering;Yanbian Korean Autonomous Prefecture of Agricultural Sciences;;A Comparative Study on Effective Composition Among Different Varieties of Aloe vera[J];北方园艺;2015-24
2 ZHANG Qiao-hui;WANG Jian-zhong;PANG Jin-hui;CUI Jie;YANG Zhe;LUO Xing-wu;Science and Technology College of Hubei University for Nationalities;Beijing Key Laboratory of Forest Food Processing and Safety;College of Biological Sciences and Technology,Beijing Forestry University;;Antioxidative activity and physical property of polysaccharide from Ledum palustre L.[J];食品与机械;2015-05
3 LV Ming-sheng;WANG Shu-jun;FANG Yao-wei;JIAO Yu-liang;LIU Shu;LIU Yuan;XU Yan;School of Marine Science and Technology,Huaihai Institute of Technology;Jiangsu Marine Resources Development Research Institute;Co-Innovation Center of Jiangsu Marine Bio-industry Technology,Huaihai Institute of Technology;;Hydrolyzate of corn starch by marine cold- adaptedα-Amylase and its biological activity[J];食品工业科技;2015-23
4 Chang Xiaoxiao;Jiang Linshu;Key Laboratory for Dairy Cow Nutrition/College of Animal Science and Technology,Beijing University of Agriculture;;Research Progress of Grape Seed Proanthocyanidin Biological Function and Its Application in Animal Product[J];中国农学通报;2015-11
5 LIU Haiying;FAN Liushibo;Agricultural Institute of Tangshan;Tianjin Baodi No.4 High School;;Protective Effects of Pleurotus eryngii Polysaccharides on S180 Tumor-Bearing Mice[J];食品科学;2015-03
6 Wang Qunfeng;Liang Chaozhao;Zhu Jinsong;Department of Urology,Anqing Municipal Hospital,Anqing Hospital affiliated Auhui Medical Univrsity;;Small cell carcinoma of the prostate(report of 2 cases and review of the literrature)[J];国际泌尿系统杂志;2014-05
7 WEI Jie;WU Cui-yun;JIANG Yuan;WANG He-li;College of Plant Science, Tarim University;Xinjiang Production and Construction Corps Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin;;Sample Preparation Optimization for Determination of Soluble Sugar in Red Jujube Fruits by Anthrone Method[J];食品科学;2014-24
8 ZHU Qiao-Ling;YU Wei;Ningbo Yinzhou Measurement and Test Center for Quality and Technique Supervising (Food Safety Testing Center of Yinzhou District);;Determination of content of total sugar in cake by anthrone-sulfuric acid method[J];食品安全质量检测学报;2014-05
9 ;The progress of flower pigment anti-cancer[J];吉林医药学院学报;2014-02
10 JING Yuan-chao;ZHAO Huan-xin;BAI Hong;Institute of Materia Medica,Shandong Academy of Medical Sciences;School of Medicine and Life Sciences,University of Jinan,ShandongAcademy of Medical Sciences;;Research progress of Diaphragma juglandis Fructus[J];药学研究;2014-03
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 YOU Yu-Hong, LIN Zhi-BinDepartment of Pharmacology, School of Basic Medical Science, Peking University Health Science Center, Beijing 100083, China;Protective effects of Ganoderma lucidum polysaccharides peptide on injury of macrophages induced by reactive oxygen species[J];Acta Pharmacologica Sinica;2002-09
2 Chen Jianji,Wu Zhiqiang, (Fujian Medical University,Laboratory of Snake Venom Research 350004) Hu En,Lin Zhiwei et al (Fujian Colloege of Traditional Chinese Medicine 350003);Studies on the Pharmacological Effects of the Polysaccharides of Ganoderma Lucidum Ⅰ.Anticancer,Antithrombosis and anticoagulation of blood[J];海峡药学;2000-01
3 Zhang Chuankal,Yuan Shengrong,Liu Jinxue(Department of Pharmacology,Capital University of Medical Sciences,Beijing 100054);Effect of Cordyceps Sinensis (CS) and Paecilomyces Sinensis (PS) on Immune Function in Mice[J];中药药理与临床;1998-03
4 Chen Fuxiang; Liu Jingxing; Lu Deyuan(Department of Microbiology, Shanghai Second Medical University, 200025);The Effects of Sophora Flavescens Alkaloids (SFA) on Coxsackie Virus B3(CVB3)in Vitro and a Preliminary Study of Its Mechanism[J];中华实验和临床病毒学杂志;1995-02
5 Bao Tiantong Wang Guifen Yang Jialu Institule of Materia Medica,Chinese Academy of Medical Sciences,Beijing;Pharmacological Actions of Cordyceps sinensis[J];中西医结合杂志;1988-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved