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Study on the Antiasthmatic Effects of Essential Oil from Centipeda minima

CHEN Qiang1,ZHOU Chunquan2,ZHU Bifeng2,PENG Huayi3,NI Feng2(1.Fujian University of Traditional Chinese Medicine,Fuzhou 350003,China;2.Fujian Academy of Traditional Chinese Medicine and Pharmacy,Fuzhou 350003,China ;3.Fujian Institute of Medical Sciences,Fuzhou 350001,China)  
OBJECTIVE To observe the antiasthmatic effects of the essential oil from centipeda minima.METHODS Used the animal model of spray-induced asthma and isolated tracheal smooth muscle of guinea pig to determine the antiasthmatic effects of the oil.RESULTS The essential oil significantly prolonged asthma latency and gasping on the guinea pig model of spray-induced asthma by ACH HT.The oil also inhibited the constriction of tracheal smooth muscle in vitro.CONCLUSION The essential oil has a good therapeutic effect on asthma.
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